Results 101 to 110 of about 608,359 (265)

Adaptive Policies for Sequential Sampling under Incomplete Information and a Cost Constraint [PDF]

, 2012
We consider the problem of sequential sampling from a finite number of independent statistical populations to maximize the expected infinite horizon average outcome per period, under a constraint that the expected average sampling cost does not exceed an
Burnetas, Apostolos, Kanavetas, Odysseas
core  

Accelerated group sequential sampling

Journal of Applied Probability
AbstractWe propose a novel and unified sampling scheme, called the accelerated group sequential sampling scheme, which incorporates four different types of sampling scheme: (i) the classic Anscombe–Chow–Robbins purely sequential sampling scheme; (ii) the accelerated sequential sampling scheme; (iii) the relatively new k-at-a-time group sequential ...
Jun Hu, Yan Zhuang
openaire   +1 more source

Multiple visual objects are sampled sequentially

PLOS Biology, 2017
When acting in a complex visual environment, it is essential to be able to flexibly allocate attention to parts of the visual scene that may contain goal-relevant information. The paper by Jia et al. provides novel evidence that our brains sequentially sample different objects in a visual scene.
Ole Jensen, Marlies E. Vissers
openaire   +4 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Controlling for survey costs when estimating covariances between Pathak estimators in fixed-budget sequential sampling

Journal of Economics and Management
Aim/purpose – This work aims to assess stochastic properties of finite population mean estimators under Pathak’s fixed-cost sequential sampling scheme by deriving their covariance and proposing its estimator.
Szymoniak-Książek Krzysztof, Gamrot Wojciech   +1 more
doaj   +1 more source

Choice history biases subsequent evidence accumulation

eLife, 2019
Perceptual choices depend not only on the current sensory input but also on the behavioral context, such as the history of one’s own choices. Yet, it remains unknown how such history signals shape the dynamics of later decision formation.
Anne E Urai, Jan Willem de Gee, Konstantinos Tsetsos, Tobias H Donner   +3 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Sequential sampling from memory underlies action selection during abstract decision-making. [PDF]

Curr Biol, 2022
Shushruth S, Zylberberg A, Shadlen MN.
europepmc   +1 more source