Results 51 to 60 of about 222,402 (275)

Nonparametric and Semiparametric Group Sequential Methods for Comparing Accuracy of Diagnostic Tests [PDF]

open access: yes, 2007
Comparison of the accuracy of two diagnostic tests using the receiver operating characteristic (ROC) curves from two diagnostic tests has been typically conducted using fixed sample designs.
Emerson, Scott S.   +2 more
core   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

GraphLab: A New Framework for Parallel Machine Learning [PDF]

open access: yes, 2010
Designing and implementing efficient, provably correct parallel machine learning (ML) algorithms is challenging. Existing high-level parallel abstractions like MapReduce are insufficiently expressive while low-level tools like MPI and Pthreads leave ML ...
Bickson, Danny   +5 more
core   +3 more sources

Gaussian process surrogates for failure detection: a Bayesian experimental design approach

open access: yes, 2015
An important task of uncertainty quantification is to identify {the probability of} undesired events, in particular, system failures, caused by various sources of uncertainties.
Li, Jinglai, Lin, Guang, Wang, Hongqiao
core   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait   +23 more
wiley   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Enhancing Nonverbal Communication Through Virtual Human Technology: Protocol for a Mixed Methods Study

open access: yesJMIR Research Protocols, 2023
BackgroundCommunication is a critical component of the patient-provider relationship; however, limited research exists on the role of nonverbal communication.
Analay Perez   +9 more
doaj   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle   +5 more
wiley   +1 more source

Sequential sampling of soybean and beans seeds for Sclerotinia sclerotiorum detection (Lib.) DeBary

open access: yesJournal of Seed Science, 2014
This study aimed to verify the efficiency of a sequential sampling plan for bean and soybean seeds, in the Sclerotinia sclerotiorum detection. Firstly the heterogeneity of Pérola and Bolinha Bean cultivars lots samples and IAC-Foscarin soybean was ...
Alessandra de Lourdes Ballaris   +3 more
doaj   +1 more source

Financial Burden Associated With Hospitalisation Among Families of Childhood Brain Tumours in Australia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Families of children with cancer experience significant financial strain, even with universal healthcare. Indirect costs, such as productivity losses and non‐medical expenses, are rarely included in economic evaluations, and little is known about how effectively financial aid programmes alleviate this burden. Childhood brain tumours
Megumi Lim   +8 more
wiley   +1 more source

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