Results 41 to 50 of about 1,918 (217)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

The Precision Validation of the Precise Baseline Determination for Satellite Formation [PDF]

open access: yesJournal of Astronomy and Space Sciences, 2011
The needs for satellite formation flying are gradually increasing to perform the advanced space missions in remote sensing and observation of the space or Earth.
Jong-Yeoun Choi, Sang-Jeong Lee
doaj   +1 more source

Sequentially Compact, Franklin-Rajagopalan Spaces [PDF]

open access: yesProceedings of the American Mathematical Society, 1987
A locally compact T 2 {T_2}
Nyikos, Peter J., Vaughan, J. E.
openaire   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Sequential orders of adjunction spaces

open access: yesLe Matematiche, 1998
See directly the ...
Ji-Cheng Hou
doaj  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Sequential Remote Brightenings and Co-spatial Fast Downflows during Two Successive Flares

open access: yesThe Astrophysical Journal, 2023
Remote brightenings often appear at the outskirts of the active regions of solar eruptive events. Nevertheless, their origin remains to be ascertained. In this study, we report imaging and spectroscopic observations of sequential remote brightenings with
B. T. Wang   +4 more
doaj   +1 more source

Sequential Designs for Filling Output Spaces

open access: yesTechnometrics, 2023
Space-filling designs are commonly used in computer experiments to fill the space of inputs so that the input-output relationship can be accurately estimated. However, in certain applications such as inverse design or feature-based modeling, the aim is to fill the response or feature space.
Shangkun Wang   +3 more
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

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