FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Clinical Outcomes of Sequential Distalization with Clear Aligners: A Systematic Review and Meta-Analysis. [PDF]
Dent J (Basel)Baxmann M, Zsoldos M, Kárpáti K.
europepmc +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Median Effective Concentration of Ropivacaine for Ultrasound-Guided T<sub>11</sub> Thoracic Paravertebral Block in Patients with End-Stage Renal Disease: A Dixon Up-and-Down Dose-Finding Study. [PDF]
Drug Des Devel TherMa J, Cao J, Wang X, Li H, Xu W, Niu Z.
europepmc +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
The association between intimate partner violence exposure and post-traumatic stress symptoms among clinical nurses in Guangdong province: Sequential indirect associations through psychological resilience and emotional exhaustion: a multicenter cross-sectional study. [PDF]
Medicine (Baltimore)Wang HH, Liu LX, Dai Y, Ye MX, Wu M.
europepmc +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
New frontiers in the p-hacking practices: assessing the effect of data peeking practice on type-I error rate through computational modeling. [PDF]
Front PsycholFreuli F, Noventa S, Lombardi L.
europepmc +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Sequential FIB-4-based testing limits detection of fibrotic MASLD despite optimized ELF thresholds. [PDF]
Hepatol CommunAllen AM +9 more
europepmc +1 more source