Prognostic Nutritional Index (PNI) in Patients With Diabetes and Sepsis: A Cross-Sectional Study. [PDF]
Patro S +7 more
europepmc +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Psychological mechanisms underlying employability among Chinese university students: a sequential mediation model and gender invariance analysis. [PDF]
Chang H, Yan G, Guo J.
europepmc +1 more source
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
C-reactive Protein-Albumin-Lymphocyte (CALLY) Index in Patients With Sepsis: An Observational Study. [PDF]
Patro S +6 more
europepmc +1 more source
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
Perceptual Design and Evaluation of a Forearm-Based Vibrotactile Interface for Transfemoral Prosthetic Feedback. [PDF]
Karimi M +4 more
europepmc +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Determination of Median Effective Concentration (EC<sub>50</sub>) of Ropivacaine with Adjuvant Dexmedetomidine When Using the Dural Puncture Epidural Technique for Labor Analgesia: An Up-Down Sequential Allocation Study. [PDF]
Wang XY +5 more
europepmc +1 more source

