Results 191 to 200 of about 268,793 (310)

Delta Sequential Organ Failure Assessment Within the First 24 Hours as a Predictor of Mortality in Critically Ill Surgical Patients: A Retrospective Study. [PDF]

Cureus
Tiwari R, Chauhan R, Patel NB.
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

How can innovative trials in juvenile idiopathic arthritis serve the unmet needs of patients? [PDF]

Arthritis Res Ther
Bennett JL, Sen ES, Ramanan AV.
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Efficacy of AC-T Versus TAC Neoadjuvant Chemotherapy for Locally Advanced Breast Cancer: A Retrospective Analysis. [PDF]

Int J Breast Cancer
Mirzania M, Anari F, Emami SAH, Roudini K, Karimi M, Saleh K, Mortezazadeh M, Khajeh-Mehrizi A.   +7 more
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Differences in characteristics of two aspects of procedural learning in action video game players. [PDF]

PeerJ
Guo W, Tao T, Jiang J, Wang B.
europepmc   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Association between creative self-efficacy and innovation literacy among undergraduate nursing students: a correlation analysis. [PDF]

Front Public Health
Lyu R, Zhou Z, Wang Y, Xu M, Zhang N, Xu F, Wang J, Chu Z, Li H, Wu J.   +9 more
europepmc   +1 more source

Performance evaluation and design method for statistical failure detection system using modified sequential probability ratio test.

Journal of the Japan Society for Aeronautical and Space Sciences, 1988
HASHIMOTO, Takeshi, KIMURA, Haruo
openaire   +2 more sources