Results 271 to 280 of about 268,793 (310)
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Statistical analysis and robust design of circularly polarized antennas using sequential approximate optimization

2018 22nd International Microwave and Radar Conference (MIKON), 2018
In the paper, reliable yield estimation and tolerance-aware design optimization of circular polarization (CP) antennas is discussed. We exploit auxiliary kriging interpolation models established in the vicinity of the nominal design in order to speed up the process of statistical analysis of the antenna structure at hand.
Slawomir Koziel, Adrian Bekasiewicz
openaire   +1 more source

Multi-objective genetic algorithm in reliability-based design optimization with sequential statistical modeling: an application to design of engine mounting

Structural and Multidisciplinary Optimization, 2019
The present study explores reliability-based design optimization (RBDO) using multi-objective genetic algorithm (MOGA) in the context of practical engineering design. The reliability analysis is carried out using a most probable point-based method with first-order sensitivities.
Juhee Lim   +4 more
openaire   +1 more source

Improving the fermentation medium for Echinocandin B production. Part I: sequential statistical experimental design

Process Biochemistry, 2001
Abstract Sequential statistical experimental designs (Plackett–Burman, factorial, response surface and ridge analysis) were used to improve the medium for the production of Echinocandin B (ECB) by Aspergillus nidulans . Special attention is given to the ridge analysis, a search and optimization technique which can be applied to second-order models ...
A.R. Cockshott, Gary R. Sullivan
openaire   +1 more source

Statistical Inference after an Adaptive Group Sequential Design: A Case Study

Drug Information Journal, 2010
The adaptive group sequential design of Lehmacher and Wassmer allows fully flexible redetermination of sample size after each of a predetermined number of interim looks. Study 02CLLIII, a large, randomized, multicenter trial in chronic lymphocytic leukemia, was based on this approach, with five planned analyses. The study terminated for efficacy at the
openaire   +1 more source

Statistical Metamodeling and Sequential Design of Computer Experiments to Model Glyco-Altered Gating of Sodium Channels in Cardiac Myocytes

IEEE Journal of Biomedical and Health Informatics, 2016
Glycan structures account for up to 35% of the mass of cardiac sodium ( Nav ) channels. To question whether and how reduced sialylation affects Nav activity and cardiac electrical signaling, we conducted a series of in vitro experiments on ventricular apex myocytes under two different glycosylation conditions, reduced protein sialylation (ST3Gal4(-/-))
Dongping Du   +3 more
openaire   +2 more sources

Forming an optimum experimental design for statistical estimation of the probability of a random event using random sequential sampling

Measurement Techniques, 2012
It is proposed that multiple measurements be treated as a random sequential sample for probability estimates and a measurement procedure based on a sequential plan is constructed which will ensure fulfillment of specified limits on the probabilities of type 1 and type 2 errors with a minimum sample volume.
N. G. Nazarov, M. V. Zelenkova
openaire   +1 more source

Statistical Methods for Sequential Monitoring and Incorporating Real-World Evidence in Bayesian Clinical Trial Design

2021
In the first part of the dissertation, we present a Bayesian framework for sequential monitoring that allows for use of external data, and that can be applied in a wide range of clinical trial applications. Monitoring priors are defined using the family of generalized normal distributions which comprise a flexible class of priors, naturally allowing ...
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Production and sequential optimization of Bacillus subtilis MF467279 pullulanase by statistical experimental designs and evaluation of its desizing efficiency

Biocatalysis and Agricultural Biotechnology, 2018
Abstract In our search for a pullulanase production from unconventional sources, Bacillus subtilis MF467279 was isolated from the desert plant species Salsola imbricate, that collected from Tur Sinai, Egypt. The optimization of pullulanase enzyme was performed in three stages.
Abeer A. Abd El Aty   +2 more
openaire   +1 more source

Refined critical boundary with enhanced statistical power for non-directional two-sided tests in group sequential designs with multiple endpoints

Statistical Papers, 2019
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Fengqing Zhang, Jiangtao Gou
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Isolation, identification and characterization of a novel Rhodococcus sp. strain in biodegradation of tetrahydrofuran and its medium optimization using sequential statistics-based experimental designs

Bioresource Technology, 2009
Statistics-based experimental designs were applied to optimize the culture conditions for tetrahydrofuran (THF) degradation by a newly isolated Rhodococcus sp. YYL that tolerates high THF concentrations. Single factor experiments were undertaken for determining the optimum range of each of four factors (initial pH and concentrations of K(2)HPO(4).3H(2 ...
Yanlai, Yao   +4 more
openaire   +2 more sources

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