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Mivacurium Infusion ED50/ED95 for Maintaining Motor Evoked Potentials During Adolescent Scoliosis Surgery Under TIVA: A Modified Dixon Up-and-Down Sequential Dose-Finding Study. [PDF]

Drug Des Devel Ther
Zhang Y, Zhang S, Wei H, Li Z, Qin H, Yuan H, Jiang X.   +6 more
europepmc   +1 more source

Positive parenting style and academic burnout in physical education teacher education students: a chain mediating model of physical activity and meaning in life. [PDF]

Front Psychol
Ma H, Liu L, Huang S, Yin Z, Liu T.
europepmc   +1 more source

Statistical Design of Sequential Decision Making Algorithms [PDF]

, 2022
Sequential decision-making is a fundamental class of problem that motivates algorithm designs of online machine learning and reinforcement learning. Arguably, the resulting online algorithms have supported modern online service industries for their data-driven real-time automated decision making.
Chi-hua Wang (12469251)
core   +5 more sources

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Statistical inference problems in sequential parallel comparison design

Journal of Biopharmaceutical Statistics, 2019
The sequential parallel comparison designhas recently been considered to solve the problem with high placebo response and the required sample size in the psychiatric clinical trials. One feature with this design is that a difference between the placebo group and the drug group may also arise in the variance-covariance structure of the clinical outcome.
Yifan, Cui, Semhar, Ogbagaber, H M James, Hung   +2 more
openaire   +2 more sources

Comparison of Test Statistics for the Sequential Parallel Design

Statistics in Biopharmaceutical Research, 2010
The sequential parallel design has been proposed to improve the efficiency of clinical trials in psychiatry. The design randomizes patients into three treatment groups. Each group has two phases. The three groups are (1) placebo in the first phase followed by placebo in the second phase, (2) placebo in the first phase followed by drug in the second ...
Xiaohong Huang, Roy N. Tamura
openaire   +1 more source

Rejoinder to “Statistical inference problems in sequential parallel comparison designs”

Journal of Biopharmaceutical Statistics, 2019
In this rejoinder the authors stipulate further for two challenging issues. First, if placebo non-responders are selected simply by their response meeting a threshold, this selection may have misclassification error and consequently the treatment effect estimate may be biased, regardless of whether the estimand at the second stage is the treatment ...
Yifan, Cui, Semhar, Ogbagaber, H M James, Hung   +2 more
openaire   +2 more sources

A commentary on: statistical inference problems in sequential parallel comparison designs

Journal of Biopharmaceutical Statistics, 2019
A Sequential Parallel Comparison Design has two stages, the first comparing drug to placebo and the second comparing drug to placebo among patients who did not respond to placebo in the first stage. The paper, Statistical Inference Problems in Sequential Parallel Comparison Designs, claims that the estimate of the treatment difference in the second ...
David Alan, Schoenfeld, Gheorghe, Doros, Maurizio, Fava   +2 more
openaire   +2 more sources