Results 241 to 250 of about 268,793 (310)

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

A Pragmatic Bayesian Adaptive Trial Design Based on the Value of Information: The Value-Driven Adaptive Design. [PDF]

Med Decis Making
Dymock M, Marsh JA, Jones M, Heath A, Murray K, Snelling TL.   +5 more
europepmc   +1 more source

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang, Chengsong Yue, Zhuang Li, Xiaolei Shi, Haoxuan Zhu, Jie Yang, Linyu Li, Jiaxing Song, Shitao Fan, Gaoming Li, Wenzhe Sun, Zhixian Ye, Jiacheng Huang, Dahong Yang, Jinfu Ma, Xu Xu, Zhixi Wang, Lilan Wang, Guojian Liu, Fengli Li, Changwei Guo, Li Qi, Wenjie Zi   +22 more
wiley   +1 more source

Sequential Phage Delivery Can Outperform Cocktails by Delaying Cross-Resistance Evolution. [PDF]

Viruses
Stuart EC, Meyer JR.
europepmc   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Clinical efficacy and safety of sequential accelerated theta burst stimulation for suicidal ideation in adults with major depressive disorder: study protocol of a randomized controlled trial. [PDF]

Front Psychiatry
Leng H, Huang G, Yang Z, Sun L, Zhang G, Ren C.   +5 more
europepmc   +1 more source

Determination of the ED90 and ED99 of Liposomal versus Conventional Bupivacaine for Ultrasound-Guided Stellate Ganglion Block: A Biased-Coin Design Study. [PDF]

Drug Des Devel Ther
Yang L, Liu J, Yang Y, Zhao H, Fan Z, Yin G, Xuan Q.   +6 more
europepmc   +1 more source

Audiometric Outcomes and Longitudinal Trends of Sequential Cochlear Implantation in Adults with Bilateral Deafness: A 20-Year Single-Center Study.

Audiol Neurootol
Shen SA, Sayyid ZN, Andresen NS, Carver C, Marsiglia DD, Yeagle J, Della Santina C, Bowditch SP, Sun DQ.   +8 more
europepmc   +1 more source

Resuscitation in paediatric septic shock using vitamin C and hydrocortisone (RESPOND): The RESPOND randomised controlled trial statistical analysis plan. [PDF]

Crit Care Resusc
Gibbons KS, Raman S, Av L, Festa M, George S, Le Marsney R, Lister P, Long DA, Nallasamy K, Pak A, Carla de Souza D, Zangerl B, Schlapbach LJ, Resuscitation in Paediatric Septic Shock using Vitamin C and Hydrocortisone (RESPOND) Study Group and the Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG).   +13 more
europepmc   +1 more source