Results 231 to 240 of about 266,543 (264)
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Statistical Methods for Sequential Monitoring and Incorporating Real-World Evidence in Bayesian Clinical Trial Design

2021
In the first part of the dissertation, we present a Bayesian framework for sequential monitoring that allows for use of external data, and that can be applied in a wide range of clinical trial applications. Monitoring priors are defined using the family of generalized normal distributions which comprise a flexible class of priors, naturally allowing ...
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Production and sequential optimization of Bacillus subtilis MF467279 pullulanase by statistical experimental designs and evaluation of its desizing efficiency

Biocatalysis and Agricultural Biotechnology, 2018
Abstract In our search for a pullulanase production from unconventional sources, Bacillus subtilis MF467279 was isolated from the desert plant species Salsola imbricate, that collected from Tur Sinai, Egypt. The optimization of pullulanase enzyme was performed in three stages.
Abeer A. Abd El Aty   +2 more
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Refined critical boundary with enhanced statistical power for non-directional two-sided tests in group sequential designs with multiple endpoints

Statistical Papers, 2019
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Fengqing Zhang, Jiangtao Gou
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Isolation, identification and characterization of a novel Rhodococcus sp. strain in biodegradation of tetrahydrofuran and its medium optimization using sequential statistics-based experimental designs

Bioresource Technology, 2009
Statistics-based experimental designs were applied to optimize the culture conditions for tetrahydrofuran (THF) degradation by a newly isolated Rhodococcus sp. YYL that tolerates high THF concentrations. Single factor experiments were undertaken for determining the optimum range of each of four factors (initial pH and concentrations of K(2)HPO(4).3H(2 ...
Yanlai, Yao   +4 more
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Feasibility of improving carbohydrate content of Chlorella S4, a native isolate from the Persian Gulf using sequential statistical designs

Biofuels, 2019
Microalgal carbohydrates can serve as feedstock for bioethanol production. Environmental and/or nutritional factors influence the carbohydrate content of microalgae and optimization of culture cond...
Mahroo Seyed Jafari Olia   +3 more
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Statistical analysis and optimization of ammonia removal from landfill leachate by sequential microwave/aeration process using factorial design and response surface methodology

Journal of Environmental Chemical Engineering, 2016
Abstract The application of microwave (MW) radiation followed by aeration (A) for the purpose of ammonia removal from both synthetic solutions and landfill leachate was investigated in this study. 100 mL of synthetic solution or landfill leachate was subjected to MW radiation for 30, 45, 60, 90 and 120 s under 50 and 100% power output level and a pH ...
Sainan Dong, Majid Sartaj
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A Comparative Analysis of Sequential Active Learning Approaches: Statistical Design of Experiments versus Bayesian Optimisation

Systems and Control Transactions
As chemical processes become increasingly complex and costs of experimentation increase, understanding the practical effectiveness of Active Learning methodologies is essential. In this regard, an ongoing debate is occurring within the research community about the use of Design of Experiments (DOE) and Bayesian Optimisation (BO).
Daniel V. Batista, Marco S. Reis
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A statistical approach to adaptive parameter tuning in nature-inspired optimization and optimal sequential design of dose-finding trials

2021
Summary: Nature-inspired metaheuristic algorithms have become increasingly popular in the last couple of decades, and now constitute a major toolbox for tackling complex high-dimensional optimization problems. Using group sequential experimentation, adaptive design, multi-armed bandits, and bootstrap resampling methods, this study develops a novel ...
Choi, Kwok Pui   +3 more
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A Sequential Sampling Approach for Multi-Fidelity Surrogate Modeling-Based Robust Design Optimization

Journal of Mechanical Design, Transactions of the ASME, 2022
Cheng Yuansheng, Hu Jiexiang
exaly  

Statistical Procedure of Cohort-sequential Design as Variation of Latent Growth Modeling

Survey Research, 2019
Sehee Hong   +3 more
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