Urinary tract infection in children: what pediatrician and nephrologist have to be aware of
Urinary tract infection (UTI) is a common pathology among children, especially infants. [1] Clinical manifestations of UTI are varied and depend on the severity of the inflammatory process, age, sex and the nature of comorbidities.
I. N. Zakharova +4 more
doaj +1 more source
Neoadjuvant chemotherapy and trastuzumab versus neoadjuvant chemotherapy followed by post-operative trastuzumab for patients with HER2-positive breast cancer [PDF]
Neoadjuvant chemotherapy plus trastuzumab (NCT) increases the rate of pathological complete response (pCR) and event-free survival (EFS) compared to neoadjuvant chemotherapy (NC) alone in women with HER2 positive breast cancer (BC).
Ades, F +16 more
core +2 more sources
Induction chemotherapy in locally advanced squamous cell carcinoma of the head and neck: role, controversy, and future directions. [PDF]
BackgroundThe value of induction chemotherapy (ICT) remains under investigation despite decades of research. New advancements in the field, specifically regarding the induction regimen of choice, have reignited interest in this approach for patients with
Cohen, EEW +6 more
core +1 more source
Bayesian data assimilation to support informed decision-making in individualized chemotherapy [PDF]
An essential component of therapeutic drug/biomarker monitoring (TDM) is to combine patient data with prior knowledge for model-based predictions of therapy outcomes.
de Wiljes, Jana +4 more
core +2 more sources
Finding the right sequence of drugs
Rapidly switching between similar antibiotics may help to slow down the evolution of resistance.
Anh Huynh, Kevin B Wood
doaj +1 more source
Treatment of head and neck cancer with photodynamic therapy: results after one year [PDF]
Photodynamic therapy (PDT) is a new and promising treatment modality for the treatment of malignant disease. This paper reports the preliminary experience of our group in the use of this therapy for the treatment of tumours arising in the head and neck ...
DeJode, ML +4 more
core +1 more source
Tracking TCRß sequence clonotype expansions during antiviral therapy using high-throughput sequencing of the hypervariable region [PDF]
To maintain a persistent infection viruses such as hepatitis C virus (HCV) employ a range of mechanisms that subvert protective T cell responses. The suppression of antigen-specific T cell responses by HCV hinders efforts to profile T cell responses ...
Arvind H Patel +10 more
core +3 more sources
Sequential therapies in gastric gastrinoma
Not required for Clinical Vignette.
openaire +2 more sources
A signaling visualization toolkit to support rational design of combination therapies and biomarker discovery: SiViT [PDF]
Targeted cancer therapy aims to disrupt aberrant cellular signalling pathways. Biomarkers are surrogates of pathway state, but there is limited success in translating candidate biomarkers to clinical practice due to the intrinsic complexity of pathway ...
Boiko, Andrei +6 more
core +3 more sources
Diabetic macular edema in proliferative stage treated with anti-vascular endothelial growth factor agent and triamcinolone acetonide by laser-based strategies [PDF]
AIM: To appraise the effect of treatment for diabetic macular edema (DME) in proliferative stage with sufficient panrentinal photocoagulation (PRP) therapy and intravitreal injections (IV) Conbercept and posterior subtenon’s triamcinolone acetonide (STTA)
Gang Qiao +4 more
doaj +1 more source

