Results 131 to 140 of about 9,633,644 (314)

Liver Stiffness Directs Intrahepatic Cholesterol Accumulation Through YAP/TAZ in Metabolic Dysfunction‐Associated Steatotic Liver Disease

open access: yesAdvanced Science, EarlyView.
Liver stiffness promotes intrahepatic cholesterol accumulation by repressing LXRα through YAP/TAZ activation. Stiff matrices impair cholesterol efflux in hepatocytes, while YAP/TAZ deletion restores LXRα activity and prevents cholesterol‐induced fibrosis.
Na Young Lee   +9 more
wiley   +1 more source

Indole‐3‐Propionic Acid Improves Alveolar Development Impairment via Targeting VAMP8‐mediated SNAREs Complex Formation in Bronchopulmonary Dysplasia

open access: yesAdvanced Science, EarlyView.
This study aims to evaluate the impact of the tryptophan‐derived metabolite indole‐3‐propionic acid (IPA) on lung development and autophagic flux. IPA alleviates hyperoxia‐induced alveolar arrest by promoting autophagosome‐lysosome fusion via inhibition of VAMP8 phosphorylation, which is suggestive of a promising therapeutic target of BPD.
Beibei Wang   +14 more
wiley   +1 more source

Da1814 Ser-1(Ok345)X | 2009-12-14T10:42:57+00:00

open access: green, 2017
Avelino Javer   +11 more
openalex   +1 more source

High-efficiency trapping of nanoparticles based on SERS embedded microcavity

open access: hybrid, 2023
Yanhong Wang   +4 more
openalex   +1 more source

Gαi1/3 Is a Novel Regulatory Target for RANKL Signal Transduction and Osteoporosis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Osteoporosis, characterized by progressive bone loss and increased fracture risk, is a growing concern as the population ages. Current treatments, though advanced, remain limited, underscoring the necessity for novel therapeutic targets. Recent studies have shown that the immune system plays a key role in osteoporosis, with osteoclasts driving
Chaowen Bai   +15 more
wiley   +1 more source

Relationship between Visual Attention Patterns and Subjective Evaluations in Housing Sales Information: A Study Using Eye-Tracking Technology

open access: yesBuildings
Traditionally, studies analyzing consumer preferences in real estate have focused on measuring subjective user responses, neglecting associated physiological responses.
Carla de-Juan-Ripoll   +3 more
doaj   +1 more source

Ser o no ser anticapitalista...

open access: yesECA: Estudios Centroamericanos, 2003
No hay resúmenes disponibles. ECA Estudios Centroamericanos, Vol. 58, No. 659, 2003: 913-920.
openaire   +1 more source

Fx2146 Ser-6(Tm2146)Iv | 2009-12-17T12:44:20+00:00

open access: green, 2017
Avelino Javer   +11 more
openalex   +1 more source

Beamwidth Optimization in Millimeter Wave Small Cell Networks with Relay Nodes: A Swarm Intelligence Approach

open access: yes, 2016
Millimeter wave (mmWave) communications have been postulated as one of the most disruptive technologies for future 5G systems. Among mmWave bands the 60-GHz radio technology is specially suited for ultradense small cells and mobile data offloading ...
Ashraf, Muhammad Ikram   +4 more
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