Results 141 to 150 of about 600,641 (257)

Comparative Effectiveness of Three Myopia Control Lenses: A Multicenter, Real-World Study of 5182 Adolescents and Children in Chongqing, China. [PDF]

open access: yesTransl Vis Sci Technol
Chen X   +11 more
europepmc   +1 more source

Computationally Evidence‐Grounded Sequence‐First Design of Peptide Binders

open access: yesAdvanced Science, EarlyView.
BOND‐PEP enables controllable, sequence‐first peptide binder design by grounding generation in binding evidence retrieved for each target. It uses topology‐conditioned message passing to integrate relevant peptide examples with the target protein sequence, forming a residue‐level representation that guides the generation of diverse, target‐specific ...
Wenze Ding
wiley   +1 more source

Chemical Bond‐Orchestrated Energy Depletion to Augment Lung Cancer Chemo‐Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study grafted dichloroacetic acid (DCA) into perylenediimide (PDI) skeleton via ionic or covalent bond to create novel metabolic agent PDIC‐AC and PDIC‐NAC, explicitly elaborated the underlying energy metabolism and therapeutic mechanism, and developed a promising strategy for energy metabolism‐targeting chemo‐immunotherapy by chemical bond ...
Xuejie Zhao   +5 more
wiley   +1 more source

Self‐Amplified Activatable Fluorescent Probe for Early Diagnosis of Acute Kidney Injury and High‐Throughput Screening of Natural Protectants

open access: yesAdvanced Science, EarlyView.
The PS‐QRC nanoprobe employs L‐serine as a targeting ligand for kidney injury molecule‐1 (KIM‐1) to achieve accumulation in injured renal tissues. Upon activation by reactive oxygen species (ROS), it undergoes a self‐amplifying cascade to release fluorophores for near‐infrared fluorescence (NIRF) imaging, enabling ultra‐early diagnosis of acute kidney ...
Yahui Chen   +10 more
wiley   +1 more source

Colectiva chilena Ser&Gráfica: fundamentos para una (contra)pedagogía artística, insurrecta y creolizadora

open access: yesTrenzar
El presente artículo se centra en revisar las nuevas conexiones entre arte y pedagogía popular, abordando una discusión conceptual que permita dar fundamento a la propuesta (contra)pedagógica de la colectiva Ser & Gráfica de la que formamos parte.
Claudia Cattaneo Clemente   +1 more
doaj  

Hospitalidade de si: ser escola, ser tempo, ser livre

open access: yes, 2020
A presente pesquisa busca compreender as possibilidades de autoria em educação tendo em vista os entrelaçamentos da herança – os acontecimentos que nos antecedem – com o contemporâneo – aquilo que nos transpassa. Tal relação aparece como possibilidade de autoria conferida aos professores e aos alunos.
openaire   +1 more source

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