Results 131 to 140 of about 4,143,620 (277)
Advanced Science, EarlyView.Corynoxine exerts potent broad‐spectrum anticancer activity by directly targeting NQO1. This interaction dissociates the oncogenic NQO1‐PTPA complex, releasing PTPA to robustly activate the tumor suppressor PP2A. Consequently, downstream Raf/MEK/ERK and PI3K/AKT signaling pathways are suppressed, downregulating c‐Myc and driving tumor regression ...
Guoqing Hou +6 more
wiley +1 more source
, 1983 Duración del fragmento: 01:17:32.Alcance y contenido: Grabación sonora que recoge la entrevista realizada a Felipe González por el periodista Manuel Antonio Rico. Contiene: 00:00:12. Presentación y contextualización de la entrevista. | 00:03:44.
Cadena SER (emisora de radio, España) +1 more
core
Advanced Science, EarlyView.In this work, MSN‐BO@LUT penetrates the blood‐spinal cord barrier for luteolin delivery in spinal cord injury. The nanodrug suppresses neuroinflammation and promotes functional recovery of the spinal cord. Mechanistically, luteolin targets protein arginine N‐methyltransferase (PRMT2) to decrease toll‐like receptor 4 (TLR4) methylation, thereby ...
Yixuan Wang +11 more
wiley +1 more source
Advanced Science, EarlyView.Lai et al. find that m6A reader YTHDC1 is specifically overexpressed in triple‐negative breast cancer (TNBC) and orchestrates glucose and glutamine metabolism in an m6A‐dependent manner to confer robust adaptability to lethal metabolic stress. Leveraging YTHDC1 knockdown‐induced metabolic vulnerability, an ATF4 mRNA‐targeted nanotherapy is developed to
Zheng‐Hao Lai +12 more
wiley +1 more source
Advanced Science, EarlyView.Single‐molecule optical sensing reveals how pH and buffer molecules regulate glyphosate interactions with gold nanorods. Combined experiments and theoretical calculations show that changes in molecular charge and competition from buffer species determine whether glyphosate binds transiently or persistently.
Kulathunga Mudalige Kalani Perera +3 more
wiley +1 more source
Ser pesquisador, ser editor, ser autor [PDF]
Revista da Escola de Enfermagem da USP, 2005 openaire +2 more sources
Advanced Science, EarlyView.Non‐invasively quantitative Raman imaging with stacking‐induced charge transfer‐enhanced Raman scattering (SICTERS) enables accurate measurement of concentrations and pharmacokinetic modeling of lymphatic transport of micelles in mice. This platform allows dynamic analysis of nanoparticle transport and underpins the design of effective lymph node ...
Yunlu Li +6 more
wiley +1 more source
4t Concurs de discjòqueis (3a part)
, 1986 4t Concurs provincial de discjòqueis enregistrat per la Cadena Ser des de la Pérgola de Castelló.
Radio Castellón Cadena SER
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