Results 191 to 200 of about 9,699,369 (280)

Advanced feature selection and temporal attention mechanisms with Bi-LSTM classifier for optimizing emotion recognition in Kashmiri speech. [PDF]

Front Artif Intell
Dar GM, Delhibabu R.
europepmc   +1 more source

RaPID Selection of Backbone Macrocyclic Peptides Targeting Akt2

Angewandte Chemie, EarlyView.
Backbone macrocyclic peptide library (BMP) library was screened against Akt2 via RaPID to discover potent BMPPakti‐3 (IC50 = 34 nM). ABSTRACT Backbone‐cyclic peptides (BMPs) are an attractive class of molecules appeared in diverse natural bioactive products. However, mRNA display technology coupled with ribosomal synthesis is intrinsically inapplicable
Koki Shinbara, Ekishin Yanagi, Ayaka Aizawa, Takayuki Katoh, Hiroaki Suga   +4 more
wiley   +2 more sources

Optimizing abbreviated breast MRI protocols for the early assessment of neoadjuvant chemotherapy response in breast cancer. [PDF]

Quant Imaging Med Surg
Chen Y, Chen S, Li Y, Li X, Lin Y, Sui Y, Yu X, Hu W, Kong Q, Liu Z, Tang W, Jiang X, Guo Y.   +12 more
europepmc   +1 more source

Synergistische Entwicklungsstrategien von Inhibitoren gegen humane UDP‐Galactose‐4‐Epimerase

Angewandte Chemie, EarlyView.
Die Epimerase GalE ist essenziell für die Biosynthese von krebsrelevanten O‐GalNAc Glykanen. Wir verwenden orthogonales, strukturbasiertes Screening niedermolekularer Fragmente an, um kovalente und nichtkovalente Inhibitoren gegen GalE mit nicht mehr als 22 optimierten Verbindungen zu erhalten.
William M. Browne, Jonathan Pettinger, Teresa Weckwerth, Andrew Purkiss, Sing Hei Lok, Louisa Penicaut, Roksana Ogrodowicz, Raveena Prema, Simone Kunzelmann, Chloe Roustan, Ganka Bineva‐Todd, Saskia Pieters, Francesca Zappacosta, Alfred E. Doherty, Isobel Oram, Christelle Soudy, Robert Quinlan, Joanna Redmond, Svend Kjaer, David House, Stephane Mouilleron, Jacob T. Bush, Benjamin Schumann   +22 more
wiley   +1 more source

Ser humano o ser estético [PDF]

, 2005
Galán, Ilia
core  

AGGREGATE R&D EXPENDITURE AND ENDOGENOUS ECONOMIC GROWTH. [PDF]

M Jess Freire-Ser?
core  

Discovery of Inhibitory Active Ingredients for α-Amylase and α-Glucosidase from Raspberry (<i>Rubus idaeus</i> L.) Stems and Leaves Guided by Affinity Ultrafiltration and UPLC-QTOF-MS/MS. [PDF]

Foods
Zhao W, Yang P, Chen M, Gu D, He D.
europepmc   +1 more source

A Synergistic Inhibitor Development Strategy Against Human UDP‐Galactose‐4‐Epimerase

Angewandte Chemie International Edition, EarlyView.
The epimerase GalE is crucial for the biosynthesis of cancer‐relevant O‐GalNAc glycans. Here, we employ orthogonal, structurally enabled small molecule fragment screens to yield both covalent and non‐covalent inhibitors against GalE within no more than 22 elaborated compounds.
William M. Browne, Jonathan Pettinger, Teresa Weckwerth, Andrew Purkiss, Sing Hei Lok, Louisa Penicaut, Roksana Ogrodowicz, Raveena Prema, Simone Kunzelmann, Chloe Roustan, Ganka Bineva‐Todd, Saskia Pieters, Francesca Zappacosta, Alfred E. Doherty, Isobel Oram, Christelle Soudy, Robert Quinlan, Joanna Redmond, Svend Kjaer, David House, Stephane Mouilleron, Jacob T. Bush, Benjamin Schumann   +22 more
wiley   +1 more source

Real-World Comparison of the Effectiveness of Defocus Incorporated Multiple Segments and Myopi-X Spectacle Lenses for Myopia Control in Turkish Children: A Retrospective Study. [PDF]

Turk J Ophthalmol
Akagün N, Altıparmak UE.
europepmc   +1 more source