Results 191 to 200 of about 4,143,620 (277)

SERS in the spotlight [PDF]

Analytical Chemistry, 2006
openaire   +2 more sources

In Vitro Selection of Functional Neoproteins Containing Highly Fluorinated Cores

Angewandte Chemie, EarlyView.
The generation of neoproteins—functional proteins containing unnatural amino acids—is a key goal in synthetic biology. We develop a platform to discover neoproteins with specified bioactivity from trillion‐member sequence libraries, using genetic code reprogramming, in vitro selection and microwave peptide synthesis.
Adam Beattie, Alexander Vinogradov, Chikako Okada, Toru Sengoku, Takayuki Katoh, Hiroaki Suga   +5 more
wiley   +2 more sources

Trend of Myopia Incidence Among Adolescents (2018-2025) in Senior High School: An 8-Year Retrospective Study in Multi-Regions of China, With Projections to 2030. [PDF]

Ophthalmic Physiol Opt
Chen S, Yao L, Wan Y, Zhao C, Qi Q, Wang X, Tang Y, Ding D, Chen Z, Liu H, Zou Z, Liu Y, Qi L.   +12 more
europepmc   +1 more source

Photoactivated Platinum Complexes: Targeting Membrane Proteins and Organelles for Precision Cancer Therapy

Angewandte Chemie, EarlyView.
This review highlights an emerging anticancer approach integrating platinum agents into photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) systems, further augmented by cancer cell membrane‐ and organelle‐targeting. By directing photoactivated platinum complexes from nontargeted distribution to cancer cells or defined subcellular sites ...
Shu Chen, Qiyuan Zhou, Jiaqian Xu, Guangyu Zhu   +3 more
wiley   +2 more sources

d-serine as a metabolic immune checkpoint in the tumour microenvironment. [PDF]

EBioMedicine
Tsugaru K, Suzuki S, Miyamoto K, Murakami K, Chida A, Kato C, Fukasawa N, Shigehara A, Hasegawa M, Yoshimatsu Y, Sasabe J, Mita M, Barker N, Harada Y, Sukawa Y, Teratani T, Nakamoto N, Kawakubo H, Takabayashi K, Kato M, Yahagi N, Kondo T, Arai E, Kitagawa Y, Hirata K, Hamamoto Y, Kanai T, Sujino T.   +27 more
europepmc   +1 more source

Should I Stay or Should I Go—Leveraging an Overlooked Feature of Click‐to‐Release Chemistry for Affinity Labeling

Angewandte Chemie, EarlyView.
Click‐to‐release (C2R) chemistry is redirected from payload liberation toward ligand‐directed covalent protein labeling through a transient dihydropyridazine methide (DHP‐methide). This concept opens the way to dual‐functional systems combining covalent target engagement with controlled effector release.
Dóra Kern, Krisztina Németh, Tímea Imre, József Simon, Kitti Meggyes, Gergő Bárdos, László Petri, Márton Bojtár, Attila Kormos, Péter Kele   +9 more
wiley   +2 more sources

Utility of signal enhancement ratio on DCE-MRI for detection of residual breast cancer following surgery or neoadjuvant chemotherapy - a pilot study. [PDF]

Pol J Radiol
Johnson A, Sarawagi R, Malik R.
europepmc   +1 more source

Coordinating Mesopore Geometry and Interfacial Water Dynamics for Iron‐Site Evolution in Nitrate Electroreduction

Angewandte Chemie, EarlyView.
Mesopore geometry programs the working‐state interface of Fe single sites during nitrate electroreduction. Hexagonal channels reorganize interfacial water and accompany the reversible evolution of isolated Fe─O4‐like sites toward Fe─O─Fe‐like motifs, promoting successive hydrogenation toward NH3 with a Faradaic efficiency of 99.1%.
Xiangyang Liu, Yingji Zhao, Norman C.‐R. Chen, Kevin C.‐W. Wu, Ho Ngoc Nam, Quan Manh Phung, Asep Sugih Nugraha, Yusuke Asakura, Yusuke Yamauchi   +8 more
wiley   +2 more sources

Synthesis, X-ray structures and biological evaluation of novel α-aminophosphonate derivatives as anti-inflammatory and antioxidant agents: an integrated <i>in vitro</i> and <i>in silico</i> study. [PDF]

RSC Adv
Douib Z, K'tir H, Douib H, Cheraiet Z, Khaldi T, Khattabi L, Harkati B, Dorcet V, Pointillart F.   +8 more
europepmc   +1 more source

Broad‐Spectrum, Cell Envelope‐Active Marinocyclin Antibiotics From a Coral‐Derived Bacterium Are Effective Against Colistin‐Resistant Bacteria

Angewandte Chemie, EarlyView.
Marinocyclins, polycationic macrocyclic depsipeptides, were discovered by genome mining from the marine coral‐derived bacterium Aquimarina megaterium. The compounds have broad‐spectrum activity against gram‐positive and gram‐negative ESKAPE bacteria.
Clara Chepkirui, Sandra Silva, Jan Straetener, Chandrashekhar Padhi, Tina Keller‐Costa, Tess Lamer, Laura Reinke, Heike Brötz‐Oesterhelt, Rodrigo Costa, Jörn Piel   +9 more
wiley   +2 more sources