Results 201 to 210 of about 4,143,620 (277)

Comparative effectiveness of orthokeratology versus highly aspherical lenslets in slowing myopia progression: a retrospective study. [PDF]

Eye Vis (Lond)
Chen M, Yang X, Lei H, Song J, Tang Y, Chen X, Du Z, Han M, Mao X.   +8 more
europepmc   +1 more source

Ser médico, ser humano

Archivos Argentinos de Pediatria, 2016
openaire   +1 more source

Substrate‐Dependent Crosslinking by the Cytochrome P450 From Aminopyruvatide Biosynthesis

Angewandte Chemie, EarlyView.
Substitutions in the aminopyruvatide precursor peptide altered the C─C linkage formed from a YLY motif by the P450 ApyO to a N─C linkage in a WLY motif. Moreover, constitutional isomers crosslinked by C─C and C─O linkages were formed from YYY or YWY motifs. ABSTRACT Cytochrome P450s catalyze an array of reactions including crosslinking of aromatic side
Chandrashekhar Padhi, Dinh T. Nguyen, Lingyang Zhu, Lide Cha, Jesse W. Wald, Douglas A. Mitchell, Wilfred A. van der Donk   +6 more
wiley   +2 more sources

Novel Peptide-Triazole Conjugates: Strategic Synthesis, Antimicrobial Properties, and Molecular Docking Study. [PDF]

J Pept Sci
Bhavsar J, Tivari S, Pati SS, Bhanderi P, Makwana B, Khunt R, Kumar N, Chaturvedi VK, Singh R.   +8 more
europepmc   +1 more source

Gain‐of‐Function Engineering of the NifEN Scaffold Into a Self‐Assembling Nitrogenase

Angewandte Chemie, EarlyView.
From scaffold to enzyme: Systematic engineering of the cofactor maturation scaffold NifEN reconstructs the P→M electron relay along with cofactor coordination and proton gating at the S2B site, converting NifEN into a functional nitrogenase capable of ATP‐dependent N2 reduction both in vitro and in vivo.
Yimo Yang, Chi Chung Lee, Steve Ortiz, Markus W. Ribbe, Yilin Hu   +4 more
wiley   +2 more sources

Ocular Dominance is Associated With Interocular Asymmetry in Refractive Error and Axial Length Across Childhood and Early Adulthood. [PDF]

Ophthalmic Physiol Opt
Harrington SC, Lingham G, Loughman J, Flitcroft I, Mackey DA, Moore M.   +5 more
europepmc   +1 more source

Adenylation Domain Engineering Enables Biosynthesis of an Improved Polymyxin Antibiotic

Angewandte Chemie, EarlyView.
To enable incorporation of l‐2‐aminodecanoic acid into polymyxin by fermentation, a single Trp‐to‐Ala substitution is rationally introduced into the adenylation‐domain residue of its nonribosomal peptide synthetase (NRPS) and efficiently switches substrate selectivity. The engineered strain produces biologically active Ada‐polymyxin, demonstrating that
Maximilian Müll, Pia Lanvers, Giulia Ravagnan, Kilian Klaus, Olena Nosovska, Ivan Vilotijevic, Jochen Schmid, Hajo Kries   +7 more
wiley   +2 more sources

Centile curves of refraction in children and adolescents aged 5-18 in Hubei Province: a study based on GAMLSS to predict refraction development. [PDF]

Int J Ophthalmol
Yi BX, Yu LR, Gong Q, Ye MH, Zhang Y, Luo G, Gong J, Xing YQ, Zhou LH.   +8 more
europepmc   +1 more source