Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Ser indio, ser negro, ser mestizo
Chasqui, 1991 ----
Robles, Jaime, Little, Paul
openaire +2 more sources
El ser humano como ser ocupacional [PDF]
, 2008 Editoria
Santos-del-Riego, Sergio
core +2 more sources
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Parallel imports, innovations and national welfare: The role of the sizes of the income classes and national markets for health care. [PDF]
, 2008 This paper shows that regardless of any intra-country income differences, parallel imports result in a lower level of health-care innovation but, contrary to popular as well as conventional theoretical wisdom, a lower price in the Third World compared to
Acharyya, Rajat +1 more
core
Sustainable bioplastics manufacturing from renewable sources
FEBS Open Bio, EarlyView.Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto +6 more
wiley +1 more source
De lo nuevo a lo otro en el pensamiento de Heidegger
Studia Heideggeriana, 2023 El presente artículo parte de la necesidad de reflexionar sobre la experiencia de lo nuevo en la historia humana y encuentra en el pensar heideggeriano sobre el comienzo y sobre el otro comienzo, en particular, un camino reflexivo que permite sincerar ...
Maribel Martina Cuenca Espinoza
doaj +1 more source
On the Design of a Novel Joint Network-Channel Coding Scheme for the Multiple Access Relay Channel
, 2012 This paper proposes a novel joint non-binary network-channel code for the Time-Division Decode-and-Forward Multiple Access Relay Channel (TD-DF-MARC), where the relay linearly combines -- over a non-binary finite field -- the coded sequences from the ...
Crespo, Pedro M. +2 more
core +1 more source
Mamey (Mammea americana L.) in Martinique Island : un patrimonio para ser valorizados [PDF]
, 2007 Introduction. Mamey (Mammea americana L., Clusiaceae) was present in Martini-que before the Spanish colonization. Its distribution area includes tropical America and the Carib-bean.
Akamine +7 more
core +1 more source