Results 131 to 140 of about 3,483,915 (288)
La educación en Colombia debe ser un derecho fundamental análisis del programa Ser Pilo Paga
, 2018 This research has been organized in four chapters as follows: at the beginning, the contextualization of international phenomena that have a significant impact on the issue of education in Colombia is presented and, at the same time, seeks to establish the ideal approach to establish that education is a right.
González Colmenares, Leidy Juliana +1 more
openaire +1 more source
Advanced Science, EarlyView.This study reports the development of a fully humanized bispecific T cell engager targeting IL13RA2, a tumor‐associated antigen enriched in glioblastoma. This off‐the‐shelf immunotherapy drives potent, antigen‐dependent T cell activation and tumor killing, and prolongs survival in experimental GBM and other solid tumors models without detectable off ...
Joseph T. Duffy +16 more
wiley +1 more source
Advanced Science, EarlyView.We report a rational design strategy for STING antagonists by dual covalent targeting of Cys292/309 in its C‐terminal domain, directly preventing functional oligomerization. Through covalent warhead repurposing, we identified P005091 and revealed its unique dual‐cysteine mechanism.
Yuxuan Zhao +23 more
wiley +1 more source
Revista de Derecho Privado (Bogota. 1997), 2013 La teoría de la acción procesal en su sentido abstracto puede servir de fundamento para la construcción conceptual del derecho fundamental al acceso efectivo a la administración de justicia, puesto que solo bajo dicha concepción es posible afirmar que ...
Fredy Hernando Toscano López
doaj +2 more sources
Intimidad, consonancia y reunión originaria de los temples
Studia Heideggeriana, 2015 En el curso de 1934/35 Heidegger se refiere a cuatro momentos esenciales del temple fundamental: desplazamiento hacia los límites del ente, inserción en la existencia histórica y arraigo en la tierra y el suelo natal, apertura del ente en conjunto como ...
Roberto J. Walton
doaj
Advanced Science, EarlyView.This study investigates how CTCs survive varying shear stress during hematogenous metastasis. We uncover a self‐protection mechanism, by which non‐adherent CTCs adapt to high shearing milieu through accumulated cytoplasmic myosin‐mediated disruption of myosin‐actin binding, attenuating force transmission into chromatin to protect CTCs from shear ...
Cunyu Zhang +10 more
wiley +1 more source
Veritas, 2018 Pretendemos analisar neste artigo o fundamento ontofenomenológico do conhecimento em L’être et le néant (1943). Como veremos, o conhecimento será concebido a partir de uma negação de tipo interna definida como relação ontológica fundamental entre ser ...
Fujiwara, Gustavo
doaj
Millimeter‐Scale Dual‐Opposing RNA‐Gradient Hydrogel for Interfacial Gene Silencing
Advanced Science, EarlyView.A branched microfluidic platform enables the fabrication of millimeter‐scale hydrogels with dual‐opposing RNA‐gradients for precise spatial control of cell gene expression. This device allows for the generation of multiple constructs at once, offering potential for future engineering of complex tissue interfaces with improved physiological relevance ...
Tyler Hoffman +11 more
wiley +1 more source
Teocomunicação, 2019 Como conciliar a exclusividade salvífica do “solus Christus” com a pluralidade de ofertas soteriológicas das outras religiões é a indagação que orienta o presente estudo.
Fontana, Leandro Luis Bedin
doaj
Advances and Perspectives in Graphene‐Based Quantum Dots Enabled Neuromorphic Devices
Advanced Science, EarlyView.Graphene‐based QDs are zero‐dimensional carbon nanomaterials with pronounced quantum confinement and tunable electronic structures. Herein, we summarize their synthesis strategies and functionalization methods, and highlight their functional roles and operating mechanisms in devices, as well as recent advances in neuromorphic electronics. We anticipate
Yulin Zhen +9 more
wiley +1 more source