Results 221 to 230 of about 3,483,915 (288)
Chemical Ligation of Backbone N‐hydroxylated Peptides
Peptide backbone N‐hydroxylation enables sequence‐agnostic fragment ligation via hydroxamate O‐acyl capture and O→N acyl transfer in water. Broad tolerance of sterically demanding nucleophilic residues is observed, and reductive N─O cleavage restores the native amide bond.
Natalia Cano‐Sampaio +1 more
wiley +1 more source
This review highlights biocatalytic prenylation as a versatile strategy for tailoring the functional properties of peptides and proteins. By comparing branched isoprenoids with linear lipids, we illustrate how specific prenyl architectures modulate the behaviors of lipidated proteins within membrane environments.
Daisuke Fujinami +2 more
wiley +1 more source
Sexual and gender diversity in nursing: radicalizing knowledge and practices. [PDF]
Santos LCD, Toriyama ATM, Nichiata LYI.
europepmc +1 more source
Hidden Markov graphical models with state‐dependent generalized hyperbolic distributions
Abstract In this article, we develop a novel hidden Markov graphical model to investigate time‐varying interconnectedness between different financial markets. To identify conditional correlation structures under varying market conditions and accommodate shape features embedded in financial time series, we rely upon the generalized hyperbolic family of ...
Beatrice Foroni +2 more
wiley +1 more source
What happens, if in the synthesis of flat silver platelets, the slow deposition of silver along twinning faults is disturbed by the addition of a nobler metal? We have looked into it and found a way to fine‐tune the metal deposition in lateral and vertical direction.
Jonas Kluitmann +3 more
wiley +1 more source
Pulmonary development in Squamata: Insights from embryonic studies using micro‐CT
Abstract Background Pulmonary development in tetrapods is a complex process, especially within squamates, where single‐chambered, transitional, and multi‐chambered lungs can be found in adult animals. While the embryological development of the respiratory system of lizards and snakes was studied in a number of species between the 1830s and 1940s, the ...
Barbara G. Champini +3 more
wiley +1 more source
El ser-unos-con-otros en la ontología fundamental de Heidegger
openaire +1 more source
Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm +7 more
wiley +1 more source

