Results 31 to 40 of about 3,455,877 (273)
Antes del pensar : las aventuras del "ergo" desde Descartes hasta Heidegger [PDF]
, 1999 Desde Descartes hasta Husserl se desarrolla una figura de fundamentación filosófica que a partir del pensar autointuyente quiere alcanzar el ser mediante alguna conexión reflexiva o lógica, que en mi enunciado se simboliza con el "ergo".
Hong-Liang Song (1904536) +5 more
core +10 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
ENSINO DE CIÊNCIAS: CONCEITOS DE ECOLOGIA E EVOLUÇÃO MINISTRADOS ATRAVÉS DE OFICINAS
e-Mosaicos, 2014 DOI: 10.12957/e-mosaicos.2014.12990 Ensinar ciências é privilegiar situações de aprendizagem que possibilitem ao aluno a formação de sua bagagem cognitiva.
Larissa Marques Pires, Lucinéia Alves
doaj +1 more source
, 2011 Our photometric-hydrodynamic method is generalized to determine fundamental parameters of multiperiodic radially pulsating stars. We report 302 UBV(RI)_C Johnson-Kron-Cousins observations of GSC 4868-0831.
Barcza +22 more
core +1 more source
El ser humano naturaliter religiosus: una perspectiva teológico-fundamental
Annales theologici, 2018 El actual contexto cultural, que algunos califican como post-secular, pone en primer plano la cuestión acerca de la condición religiosa del ser humano. La filosofía de la religión, a partir de cuanto avanzado por la fenomenología y la hermenéutica acerca de la experiencia religiosa, muestra cómo no se puede sostener la exigencia veritativa de la ...
openaire +3 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Resolução problemas de estrutura aditiva por alunos de 4º ano do ensino fundamental
Espaço Pedagógico, 2017 O presente estudo teve como objetivo geral analisar a resolução de problemas de estrutura aditiva de alunos de quarto ano do ensino fundamental, visando identificar que tipos de problemas oferecem-lhes dificuldades.
Sheila Denize Guimarães
doaj +1 more source
The New SI and the Fundamental Constants of Nature [PDF]
, 2020 The launch in 2019 of the new international system of units is an opportunity to highlight the key role that the fundamental laws of physics and chemistry play in our lives and in all the processes of basic research, industry and commerce.
Martin-Delgado, Miguel A.
core +3 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source