COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
La exhibición de la intimidad como estrategia de inclusión social entre los jóvenes y adolescentes
Las comunidades virtuales, las redes sociales on line y el celular se han legitimado entre los adolescentes como las formas de inclusión social por excelencia.
Rosalía Winocur
doaj +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Metodologias para o ensino de astronomia e Física através da construção de telescópios
Este trabalho propõe a construção manual de telescópios refletores como ferramenta didática para o ensino de Física e Astronomia. Cada etapa da construção pode ser aliada a conteúdos de óptica geométrica e óptica Física com abordagens diferentes ...
Tamara de O. Bernardes +2 more
doaj +1 more source
Surface Enhanced Raman Scattering (SERS): From Fundamental Mechanism to Bio-Analytics Tools [PDF]
This review discusses the surface-enhanced Raman scattering (SERS) with efficiencies enhanced by as much as 1014-1015 fold as well as a SERS cross section on the order of 10-17-10-16 cm2/molecule. Despite the existing controversy on the origin of the enhancement, SERS effect offers new opportunities for spectroscopic detection of single molecules near ...
Xiao Zhi, Li Lin, Di Chen
openaire +2 more sources
Sustainable bioplastics manufacturing from renewable sources
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto +6 more
wiley +1 more source
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
É eticamente aceitavel o uso de recém cadaveres no ensino de procedimentos médicos?
A utilização de recém-cadáveres no ensino de procedimentos médicos ocorre com frequência desconhecida. Na área cirúrgica o treinamento de habilidades tem fundamental importância devido à necessidade de procedimentos invasivos próprios dos cirurgiões ...
José Marques Filho
doaj +1 more source
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
El carisma de un joven profesor inconformista: la fuerza y la magia de Ser y tiempo
Todavía hoy en día, Ser y tiempo sigue siendo un título mágico, compuesto de dos palabras intrigantes que, en su compleja sencillez, intenta repensar la pregunta fundamental de la historia de la filosofía: la pregunta por el ser.
Jesús Adrián Escudero
doaj +1 more source

