Results 131 to 140 of about 278,248 (259)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Family Functioning and Kinesiophobia in Patients After Pacemaker Implantation: A Cross-Sectional Serial Mediation Study of Pain and Pain Catastrophizing. [PDF]

J Pain Res
Xu M, Zhang T, Ma J, Li Y, Jia W, Yao L.
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Coherence: a new approach for analyzing interrelated serial data

Human Biology and Public Health
Background Serial public health data may or may not reflect living conditions, political background and/or certain targeted health interventions. Yet, the effect of political events and/or health interventions that only last for a few years or a single ...
Rebekka Mumm, Detlef Groth, Michael Hermanussen   +2 more
doaj  

Numerical backup protection scheme based on alienation indices of voltage and current measurements practically applied to synchronous generators. [PDF]

Sci Rep
Mahmoud RA, Salama MAE.
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Effects of social support and type D personality, with serial mediation by psychological resilience and positive coping styles - a cross-sectional study: Subjective well-being in hemodialysis patients. [PDF]

Medicine (Baltimore)
Xie C, Zhang Y, Xie J, Xu J.
europepmc   +1 more source

On the Distribution of the Serial Correlation Coefficient

The Annals of Mathematical Statistics, 1945
openaire   +3 more sources

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Prior Trial Effects on Working Memory in Schizophrenia, Bipolar Disorder, and Healthy Control Individuals. [PDF]

JAMA Psychiatry
Bansal S, Bae GY, Barch DM, Erickson M, Carter CS, MacDonald AW, Luck SJ, Gold JM.   +7 more
europepmc   +1 more source