Results 71 to 80 of about 278,248 (259)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Validation and Feasibility of Echocardiographic Assessment of Systemic Right Ventricular Function: Serial Correlation With MRI. [PDF]
Front Cardiovasc Med, 2021 Zandstra TE +9 more
europepmc +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
A remark on serial correlation in maximum likelihood [PDF]
Journal of Econometrics, 1983 Abstract Maximum likelihood estimation can be consistent and asymptotically normal despite serial correlation in the residuals. The usual estimator of the asymptotic covariance of the parameter estimator is inconsistent, but an alternative consistent estimator is derived.
openaire +3 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Analyzing the Trends of Precipitation and Drought in Some Semi-Arid toHumid Regions of Iran
علوم آب و خاک, 2018 In this study, the trends of changes of the standardized precipitation index in a 12-month timescale (SPI-12) and seasonal and annual precipitation were investigated in 21 humid and semi-arid stations of Iran during the 1976-2014 time period.
M. Nouri, M. Homaee, M. Bannayan
doaj
Liquidity Risk and Hedge Fund Performance Evaluation
Nauki o Finansach, 2021 In this article the author uses two models, a lagged-effects model and a serial correlation model, which identify potential liquidity risk in hedge fund portfolios.
Richard H. Horne Van
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Frontiers in PsychologyIntroductionWith the deepening of China’s urbanization process and the popularization of digital media, significant changes have occurred in the cultural participation behaviors and psychological adaptation methods of urban youth.
Dongyang Yuan
doaj +1 more source