Results 111 to 120 of about 556,751 (253)
In the context of vocational education’s digital transformation, enhancing teachers’ digital literacy is critically important. However, existing research has focused primarily on external interventions such as infrastructure and training, often ...
Yiwen Zhang +6 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
BackgroundGenerative artificial intelligence is profoundly reshaping knowledge work, yet the cognitive mechanisms through which AI use relates to employee innovation performance remain underexplored.ObjectiveIntegrating Conservation of Resources theory ...
Da Teng +3 more
doaj +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
IntroductionThe rapid evolution of artificial intelligence (AI) has transformed higher education by providing unprecedented support for AI-assisted learning.
Yanling Lan, Sihang Liu, Hao Chen
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Some Consideration on the Mediation Contract [PDF]
Interaction between people is the most different and diverse, from harmony to the conflict , so that when conflicts arise between them, because they are bound by a contract, the legal system offers a wide range of possibilities for settlement, the ...
Stoica, Veronica
core
Mediation: Ein Meta-Modell [PDF]
The Mediation Meta-Model introduced in this article provides a framework for understanding a range of mediation practice models and their relationship to each other and to other ADR processes.
Alexander, N. M., ALEXANDER, Nadja
core
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source

