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Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source

Flow diagram of serial–parallel mediation model with ACE as predictor variable.

Flow diagram of serial–parallel mediation model with ACE as predictor variable.
Alessandro Carollo (11507042) +8 more
core +1 more source

Exploring the formation of learning burnout among college students in AI context: a serial mediation mechanism of AI dependence and addiction based on I-PACE model

Frontiers in Computer Science
IntroductionThe rapid evolution of artificial intelligence (AI) has transformed higher education by providing unprecedented support for AI-assisted learning.
Yanling Lan, Sihang Liu, Hao Chen
doaj +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source

Serial control of phonology in speech production [PDF]

The aim of this thesis is to further our understanding of the processes which control the sequencing of phonemes as we speak: this is an example of what is commonly known as the serial order problem.
Vousden, Janet
core

Grit and Academic Self-Efficacy as Serial Mediation in the Relationship Between Growth Mindset and Academic Delay of Gratification: A Cross-Sectional Study

, 2023
Hui Zhao,1 Yan Li,1,2 Luyuan Wan,1,3 Ke Li1 1Faculty of Education, Henan Normal University, Xinxiang, People’s Republic of China; 2Sanzhang Primary School, Nanyang, People’s Republic of China; 3Central School of Huolong Town, Xuchang, People’s Republic ...
Li Y, Wan L, Li K, Zhao H
core

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source

Flow diagram of serial–parallel mediation model with BCE as predictor variable.

Flow diagram of serial–parallel mediation model with BCE as predictor variable.
Alessandro Carollo (11507042) +8 more
core +1 more source

Mediation Essentials

, 2016
Mediation is one of the most frequently used alternative dispute resolution processes worldwide. Mediation provides faster, cheaper, and better solutions than a traditional court decision can. Benefits are
International Finance Corporation
core +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source

serial mediation
loneliness
sleep quality

entrepreneurial intention
perceived social support