Results 51 to 60 of about 14,246,728 (251)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Interactive effects between flexible and rigid control of eating behavior on body weight: a moderated serial multiple mediation model

, 2017
Background Cognitive restraint of eating can be subdivided into rigid control and flexible control of eating behavior. Flexible control appears to be a more favorable dieting strategy as it relates to lower disinhibited eating and body mass index (BMI),
Adrian Meule
core   +1 more source

Cumulative trauma and perceived community resilience: A serial mediation model

, 2023
Communities affected by cumulative trauma can experience negative psychological reactions but also posttraumatic growth and community resilience, which promote adaptation and preparation for future traumatic events. This study aims to investigate ...
Olcese M., Cardinali P., Migliorini L., Antichi L.   +3 more
core   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A Serial Mediation Model of the Brain Drain Perceptions Among Health and Tourism Students

AIM: It was aimed to explore the serial mediation role of self-efficacy and financial anxiety levels in the impact of health and tourism students’ life satisfaction on brain drain perceptions.
Gülseren Yurcu, Dilek Hale Aybar, Ayşegül Ilgaz, Sebahat Gözüm   +3 more
core   +1 more source

How physical activity enhances academic engagement in middle school: a serial mediation model of interpersonal relationships and academic support

Frontiers in Psychology
IntroductionAcademic engagement is a critical aspect of adolescent development. Understanding the mechanism of academic engagement will help to take effective measures to improve the academic engagement of middle school students. This study used a serial
Junmin Zhang, Yongfeng Liu, Xiaogang Zhang, Shuiyou Hu   +3 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

An empirical test of Holmes and Holmes serial murder typology. [PDF]

, 2004
This article presents the results of an empirical test of Holmes and Holmes’s serial murder classification scheme. Crime scene evidence from 100 U.S. serial murders, each the third in a distinct series, was content analyzed.
David V. Canter, Canter, David V.
core   +1 more source

Mindfulness, Gratitude, and Self-Compassion as Sequential Mediators Between Life Stress and the Outcomes of Stress Response and Mental Well-Being among Korean Nursing Students

SAGE Open
Stress adversely affects physical and mental health, particularly among nursing students. This study examined a serial mediation model in which mindfulness promotes gratitude and self-compassion, which in turn mediates the effect of life stress on stress
Young Im Cho, Hyo Jin Kim, Dong Hee Kim
doaj   +1 more source