Results 71 to 80 of about 14,246,728 (251)

Mediation and peace [PDF]

open access: yes, 2010
This paper applies mechanism design to conflict resolution. We determine when and how unmediated communication and mediation reduce the ex ante probability of conflict in a game with asymmetric information.
Hörner, Johannes   +6 more
core   +2 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Compelling parties to mediate: Recipe for success or slippery slope?

open access: yes, 2017
This article describes the different types of mediation that are used throughout the world and explains the advantages and disadvantages of each type.
Jordaan, Barney
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

The impact of appearance anxiety on loneliness among college students: an integrative model

open access: yesBMC Psychology
Background The widespread use of social media has made appearance anxiety increasingly prevalent among college students and has been linked with mental health concerns.
Jianbao Chang, Dehua Guo, Shiqin Dai
doaj   +1 more source

Environmental concerns, financial sacrifice, and motivation as predictors of Gen Z sustainable behaviour

open access: yesEconomics and Environment
Sustainable consumer behaviour is critical to improving the natural environment and protecting natural resources. The paper explores selected factors influencing the home sustainable behaviour of Generation Z consumers.
Marzena Lemanowicz   +5 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

How Is Bullying Victimization Associated with Depressive Symptoms Among Multicultural Adolescents in South Korea? A Serial Mediation and Network Analysis of Acculturative Stress and Ego-Resiliency

open access: yesBehavioral Sciences
Bullying victimization is consistently associated with depressive symptoms among adolescents, yet the psychological processes underlying this association remain insufficiently understood, particularly among multicultural adolescents.
Zhenping Jiang   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The impact of self-stigma on college students' attitudes toward professional psychological help-seeking: serial-mediated effects of discrimination perceptions and core self-evaluations

open access: yesFrontiers in Psychology
PurposeTo explore the role of self-stigma as predictor of college students' attitudes toward professional psychological help-seeking, as well as the separate and serial mediating roles of discrimination perceptions and core self-evaluations between the ...
Daoliang Chen   +3 more
doaj   +1 more source

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