Results 141 to 150 of about 9,522,068 (262)

A bibliometric analysis of global research in cervical cancer radiotherapy (2015-2024): trends, hotspots, and future directions. [PDF]

Transl Cancer Res
Hou Y, Gao Y, Yan WM.
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

From prognostication to implementation: the next frontier for ultrasound-guided assessment of decongestion. [PDF]

Eur Heart J Imaging Methods Pract
Koratala A, Kazory A.
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Re: Methodological Considerations in Frailty Assessment for Distal Radius Fracture Surgery. [PDF]

Geriatr Orthop Surg Rehabil
Farooq K, Nazir F.
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Residual imaging abnormalities after acute hamstring strain injury: implications for return-to-sport decision-making. [PDF]

Front Sports Act Living
Wang J, Zhao L.
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Genome Constellations Recovered Following In Vitro Co-Infection and Serial Passage of Bluetongue Virus Serotypes 1 and 16. [PDF]

Viruses
Plebani G, Salvaggiulo A, Pizzurro F, Teodori L, Leone A, Brandimarte L, Iannetta M, Pulsoni S, Vecchiato G, Casaccia C, Lorusso A.   +10 more
europepmc   +1 more source

Serial verbs

, 2018
In many languages of the world, a sequence of several verbs act together as one unit. These sequences—known as serial verbs—form one predicate and contain no overt marker of coordination, subordination, or syntactic dependency of any sort.
Aikhenvald, Alexandra Y.
core