Results 121 to 130 of about 9,522,068 (262)
Nonparametric Tests for Serial Independence Based on Quadratic Forms [PDF]
Tests for serial independence and goodness-of-fit based on divergence notions between probability distributions, such as the Kullback-Leibler divergence or Hellinger distance, have recently received much interest in time series analysis.
Panchenko, V., Diks, C.G.H.
core
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
El artículo aborda el comportamiento de la publicación científica de Humanidades Médicas, que publica los resultados científicos en el campo de las Ciencias Sociales y Humanísticas en Salud, desde enero del 2001 y con frecuencia cuatrimestral.
Jorge Luis Cabrera Cruz +4 more
doaj
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Serial Killers and the Phenomenon of Serial Murder: A Student Textbook
A superbly targeted resource for those learning about serial killings. Serial Killers and the Phenomenon of Serial Murder examines and analyses some of the best known (as well as lesser) cases from English criminal history, ancient and modern.
Wilson, David +2 more
core +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Correction Notice for "Letter from the Editors" (WSFH, Vol. 50)
In the "Letter from the Editors" for this issue (Journal of Western Society for French History (WSFH), 2024, Vol. 50, DOI 10.3998/wsfh.7119) an acknowledgment paragraph was mistakenly omitted at the time of publication. The editors regret this error.
doaj +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source

