Results 41 to 50 of about 98,828 (233)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Serials diplomacy at the ISSN International Centre: a unique and sustainable experience (1975-2015)

open access: yesCiência da Informação, 2019
In 1975, the creation of the Centre d’enregistrement des publications en série (CIEPS) / International Centre for the Registration of Serial Publications was supported by Unesco and France.
Gaëlle Béquet
doaj  

ON THE PROBLEMS OF IDENTIFICATION OF INFORMATION SOURCES BEING DISCOVERED IN THE COURSE OF CITATION STUDIES WITH THE USE OF JOURNAL CITATION REPORTS®

open access: yesСистемный анализ и прикладная информатика, 2018
During the citation study of serial publications with the use of Journal Citation Reports® (JCR) a number of items are being revealed (among others) which abbreviated titles cannot be identified with the use of the JCR itself. Typically, such sources are
V. S. Lazarev, I. V. Yurik
doaj   +1 more source

Restarting for the thrill: Behavioural addiction to entrepreneurship

open access: yesInternational Entrepreneurship Review, 2021
Objective: The aim of the article is to highlight the behavioural addiction to entrepreneurship by entrepreneurs. Research Design & Methods: We followed a qualitative design in order to ascertain the publications to date with regards to behavioural ...
Ndivhuho Tshikovhi   +2 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The management systems of books' and non-serial publications' data bases in publishing and book selling

open access: yesInformation & Media, 1997
The article deals with Information Resources Management systems. An analysis of the management systems of books' and non-serial publications' databases is discussed; Book Data, Harcourt Brace, McGraw-Hill, their software and hardware ...
Edita Sakalauskaitė
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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