Results 91 to 100 of about 88,119 (330)
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Sex in the city: the rise of soft-erotic film culture in Cinema Leopold, Ghent, 1945-1954 [PDF]
, 2015 Since the 1990s, film studies saw a disciplinary shift from approaches favoring a textual and ideological analysis of films to a broader understanding of the socio-cultural history of cinema under the banner of new cinema history.
Biltereyst, Daniël +1 more
core +1 more source
Item‐based scoring and serial position of words generated during the Category Fluency Test: differences between controls and MCI subtypes [PDF]
, 2023 Matteo De Marco, Annalena Venneri
openalex +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Convocatoria Impossibilia 10: Narración televisiva y serialidad
Impossibilia: Revista Internacional de Estudios Literarios, 2015 Call for Papers Impossibilia 10: Television Narrative and ...
Revista Impossibilia
doaj
Le son donné. Une fabrique archivistique
Tracés, 2019 This article deals with the specificities and uses of sound data produced in the particular context of an experiment led in Brussels over the last twenty years by the BNA-BBOT organization.
Séverine Janssen, Camille Noûs
doaj +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Arrigo Lora Totino, “architetto di parole”: dalle verbotetture ai cromofonemi
Lea, 2018 The paper proposes an analysis of the first phase of the artistic-literary activity of Arrigo Lora Totino, from the review Antipiugiù to the “concrete turn” of the 1960s, in relation to the diffusion of concrete experimentation in Germany and Brasil, and
Teresa Spignoli
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source