Results 81 to 90 of about 2,985 (286)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Arrigo Lora Totino, “architetto di parole”: dalle verbotetture ai cromofonemi
Lea, 2018 The paper proposes an analysis of the first phase of the artistic-literary activity of Arrigo Lora Totino, from the review Antipiugiù to the “concrete turn” of the 1960s, in relation to the diffusion of concrete experimentation in Germany and Brasil, and
Teresa Spignoli
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Seriality in the Streaming Era
Seriality in the Streaming Era explores the dynamic transformation of serialized storytelling in the digital era, where platforms like Netflix, Disney+, and Apple Podcasts have redefined how narratives are created, consumed, and experienced.
core +2 more sources
Convocatoria Impossibilia 10: Narración televisiva y serialidad
Impossibilia: Revista Internacional de Estudios Literarios, 2015 Call for Papers Impossibilia 10: Television Narrative and ...
Revista Impossibilia
doaj
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
, 2014 Persona is a public presentation of identity. One of the key values of a persona is its consistency in its presentation of the self. This article is designed to be the first exploratory steps and overview in charting the idea of seriality in relation to
David Marshall (13066161)
core
Rivista di Storia dell'EducazionePicturebooks (albums pour la jeunesse) first achieve an identity as media in their own right in the 19th century. Thanks to authors from different European countries and from the United States, the early 20th century brings about a transition from ...
Luca Ganzerla
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source