Results 91 to 100 of about 9,366 (302)

Convocatoria Impossibilia 10: Narración televisiva y serialidad

open access: yesImpossibilia: Revista Internacional de Estudios Literarios, 2015
Call for Papers Impossibilia 10: Television Narrative and ...
Revista Impossibilia
doaj  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Diagrams for Seriality [PDF]

open access: yes, 2014
Diagrams for Seriality is a book of unforgettable images and strange characters. Here the reader is thrown into a world where expectations of series and sequence are turned inside out; this story creates a narrative of haunting and mysterious affect. ‘
Chapman, Neil
core   +2 more sources

The Role of French Publications in the Evolution of Modern Picturebooks: Illustrators and Serial Characters

open access: yesRivista di Storia dell'Educazione
Picturebooks (albums pour la jeunesse) first achieve an identity as media in their own right in the 19th century. Thanks to authors from different European countries and from the United States, the early 20th century brings about a transition from ...
Luca Ganzerla
doaj   +1 more source

Seriality, Repetition and Innovation in Breaking Bad’s Recaps and Teasers

open access: yesCinergie, 2017
In this article we face some rhetorical and socio-semiotical operations that contribute to build the serial narrative ecosystems, focusing on the Breaking Bad case.
Nicola M. Dusi
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Serial recall

open access: yes, 2020
Serial memory refers to the ability to recall a novel sequence of items or events in the correct order. In the laboratory, the dominant tool used to assess this mental faculty is the immediate serial recall (hereafter, ‘serial recall’) task in which participants are given a sequence of typically verbal, visual, or spatial items that they must ...
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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