Results 101 to 110 of about 3,343,342 (268)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Наука телевидения, 2017 The article is devoted to the arrangement of the modern realities of the fabulous material by the example of the popular American TV series «Grimm» and «Once Upon a Time in a Fairytale», where through the ambivalent relationship of time and space ...
SPUTNITSKAYA N.Y. / СПУТНИЦКАЯ Н.Ю.
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Aequationes Mathematicae, 1983 Let \(L^ 2\) denote the Banach algebra of Lebesgue-integrable functions \(f: [0,\omega)\to {\mathbb{C}}\) with convolution product ''*'', \(\Omega\) a nonfinite compact subset of the right half-plane Re s\(>0\) and the space of generalized functions \(X_{\Omega}\) the completion of \(L^ 1\) with respect to the norm \[ | x|_{\Omega}=\max_{s\in \Omega}| \
openaire +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
The Transformation of a Lagrangian Series into a Newtonian Series [PDF]
Proceedings of the National Academy of Sciences, 1939 openaire +3 more sources
DYNAMIC / CHRONOLOGICAL (TIME) SERIES [PDF]
Revista Română de Statistică, 2012 Time series, which emphasize the temporal characteristic of phenomena, are an important in the context of macro-economical analyses. Specific to the dynamic series is the fact that they are defined for complexentities, characterized by a high level of ...
Constantin ANGHELACHE, Alexandru MANOLE
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Imágenes para 25 habitaciones: Office KGDVS
ARQ, 2012 A partir de una colección de habitaciones idénticas en planta y topológicamente equivalentes, tres imágenes dan cuenta de la crítica relación entre el espacio y los objetos contenidos en él, y de los matices de habitabilidad posibles en un campo neutro.A
Kersten Geers, David van Severen
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