Results 61 to 70 of about 7,852,908 (296)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Minimisasi Riak Arus Keluaran Penyearah Daya-besaran dengan Menggunakan Filter Aktif

open access: yesJournal of Mathematical and Fundamental Sciences, 2019
Sari. Suatu metode baru untuk meminimisasi riak arus keluaran penyearah daya besar dengan menggunakan filter aktif diusulkan dalam tulisan ini. Karena filter aktif terhubung parallel dengan beban, maka kapasitas arus filter aktif yang diperlukan menjadi
Pekik Argo Dahono
doaj  

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Two Degree of Freedom Resonant Structure for Robust Current Control and Active Power Filtering [PDF]

open access: yes, 2005
This paper introduces a novel two degree of freedom resonant control structure for current control in a stationary reference frame in one- or three-phase power electronics systems. The main focus is put on the design of the controller for robust tracking
N. Bajcinca   +3 more
core   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Modeling and Experimental Validation of a Single-Phase Series Active Power Filter for Harmonic Voltage Reduction

open access: yesIEEE Access, 2019
Research advances on renewable energy systems have increased the interest in the use of isolated power supplies composed of power converters based on high-frequency transformers.
Lucas Frederico Jardim Meloni   +3 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

A non-linear controller design for UPQC in distribution systems

open access: yesAlexandria Engineering Journal, 2018
In this article, a new approach based on non-linear control scheme was proposed for unified power quality conditioner (UPQC). The combination of sliding mode control and instantaneous active and reactive power theories was used to design this controller.
Mojtaba Yavari   +2 more
doaj   +1 more source

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