Results 61 to 70 of about 4,542,205 (287)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Series Form Solution to Two Dimensional Heat Equation of Fractional Order
Results in Nonlinear Analysis, 2019 In this article we develop series type solution to two dimensional wave equation involving external source term of fractional order. For the require result, we use iterative Laplace transform.
Atta Ullah, Kamal Shah, Rahmat Ali Khan
doaj
Study of the Six-Compartment Nonlinear COVID-19 Model with the Homotopy Perturbation Method
AxiomsThe current study aims to utilize the homotopy perturbation method (HPM) to solve nonlinear dynamical models, with a particular focus on models related to predicting and controlling pandemics, such as the SIR model.
Muhammad Rafiullah +3 more
doaj +1 more source
The Riemann–Liouville fractional derivative for Ambartsumian equation
Results in Physics, 2020 The Ambartsumian equation, based on the modified Riemann–Liouville fractional derivative, is analyzed in this paper. The solution is expressed as a power series of arbitrary powers and its convergence has been proven.
E.R. El-Zahar +4 more
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Exact and Approximate Solutions of A Fractional Diffusion Problem with Fixed Space Memory Length
International Journal of Applied Mathematics and Computer ScienceWe study a fractional differential diffusion equation, where the spatial derivative is expressed by the fractional differential operator with a fixed space memory length.
Klimek Malgorzata, Blaszczyk Tomasz
doaj +1 more source
Finite Series of Distributional Solutions for Certain Linear Differential Equations
Axioms, 2020 In this paper, we present the distributional solutions of the modified spherical Bessel differential equations t2y″(t)+2ty′(t)−[t2+ν(ν+1)]y(t)=0 and the linear differential equations of the forms t2y″(t)+3ty′(t)−(t2+ν2−1)y(t)=0, where ν∈N∪{0} and t∈R. We
Nipon Waiyaworn +2 more
doaj +1 more source
On Solving Some Trigonometric Series [PDF]
, 2013 This communication shows the track for finding a solution for a sin(kx)/k**2 series and a fresh representation for the Euler's Gamma function in terms of Riemann's Zeta function.
Stenlund, Henrik
core
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source