Results 61 to 70 of about 1,126,411 (268)
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Series Solution for Painlevé Equation II
Walailak Journal of Science and Technology, 2014 The Painlev'e equations are second order ordinary differential equations which can be grouped into six families, namely Painlev'e equation I, II,…, VI.
Fazle MABOOD +3 more
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
工程科学与技术, 2017 :Investigation on the stress displacement field for the plane stress disk,which is also called the Brazilian disk,has an important theoretical and practical value for elastic mechanics,rock mechanics and fracture mechanics.In order to obtain the closed ...
董世明, 李一凡, 徐积刚
doaj
Nonlinear Engineering, 2014 The two-dimensional differential transform method (DTM) is applied to solve the one-dimensional coupled heat and moisture diffusion problem for a slab with temperature-dependent thermal and moisture diffusivities, which are expressed by a linear ...
Chiba Ryoichi
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
工程科学与技术, 2007 :A new analytical method with sum function is introduced for solving problems of elasticity. The stress analysis of multi-span continuous deep beam subjected to distributed load has been performed.
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source