Results 71 to 80 of about 7,358,373 (294)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Existence of fractional order semianalytical results for enzyme kinetics model
Advances in Difference Equations, 2020 This research work investigates the existence of semianalytical solutions of a chemical kinematics model. We develop the conditions for the existence of the solutions for a proposed enzyme kinetics model, via tools of the fixed point theory.
Hussam Alrabaiah +3 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Series solution of the Smoluchowski’s coagulation equation
Journal of King Saud University - Science, 2011 AbstractThe Smoluchowski coagulation equation is a mean-field model for the growth of clusters (particles, droplets, etc.) by binary coalescence; that is, the driving growth mechanism is the merger of two particles into a single one. In this study, we consider obtaining approximate solutions of the Smoluchowski’s coagulation equation using the homotopy
Yildirim A., Koçak H.
openaire +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Regional Solutions coordinators
, 2017 "State resources are strategically aligned throughout Oregon to accomplish these goals [of community and economic development] though Regional Solutions Advisory Committees, Centers, and Teams...Coordination for these is provided by the Governor's Office"
core
Advances in Difference Equations, 2020 In this paper, we broaden the utilization of a beautiful computational scheme, residual power series method (RPSM), to attain the fractional power series solutions of nonhomogeneous and homogeneous nonlinear time-fractional systems of partial ...
Ved Prakash Dubey +4 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source