Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Críticas al «cambio climático» a partir de la evolución de la temperatura en el Atlántico Norte
El trabajo tiene como objetivo conocer la evolución de la temperatura del aire en el Atlántico Norte. Para ello, se seleccionan diez series temporales y se analizan durante el período instrumental, que en casi todas las estaciones meteorológicas abarca ...
M.ª Eugenia Pérez González +1 more
doaj
Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini +28 more
wiley +1 more source
En este artículo se presenta el estudio de una acción volátil de la Bolsa de Valores de Colombia la cual es analizada usando un modelo estadístico ARIMAX (Modelo autorregresivo integrado de media móvil con entrada exógena) y un SONFS (sistema neuro ...
José Alejandro Avellaneda González +2 more
doaj
CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source
EXTRACCIÓN DE SEÑAL Y PREDICCIÓN EN SERIES TURÍSTICAS
En los últimos años existe un creciente interés en materia de investigación turística, en un sector dinámico y de comportamiento especialmente complejo. En este escenario resulta de especial dificultad el manejo de las series temporales disponibles.
José Mondéjar Jiménez +3 more
doaj +2 more sources
SPG4 and Dementia: Expanding the Clinical Spectrum
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
Estimación de modelos de volatilidad estocática en media. aplicación en series temporales
Tradicionalmente para estimar la volatilidad de series temporales de alta frecuencia se han utilizado los modelos autorregresivos de heterocedasticidad condicionada (modelos ARCH) y su generalización (modelos GARCH).
Calvo Martín, Meri Emilia +1 more
doaj
Wheat yield prediction in Andalucía using MERIS Terrestrial Chlorophyll Index (MTCI) time series
There is a relationship between net primary production of wheat and vegetation indices obtained from satellite imaging. Most wheat production studies use the Normalised Difference Vegetation Index (NDVI) to estimate the production and yield of wheat and ...
V. Egea-Cobrero +3 more
doaj +1 more source
Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani +10 more
wiley +1 more source

