Results 81 to 90 of about 4,202,279 (295)
Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin +8 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera +20 more
wiley +1 more source
Análisis de series temporales climáticas
, 2020 The aim of the work presented below is to find a model that adjusts a climate time series in order to make more or less reliable predictions of climate behaviour in the future. In terms of methodology, the work revolves around the application of the bootstrapping technique to calculate the standard deviation bootstrap estimator on a series of dependent
openaire +1 more source
Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif +17 more
wiley +1 more source
Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay +15 more
wiley +1 more source
Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad +22 more
wiley +1 more source
EFECTO DE AUTOCORRELACIÓN EN EL MODELADO DE SERIES TEMPORALES
Anales (Asociación Física Argentina), 2013 La persistencia es una de las características más comunes de las series temporales correspondientes a fenómenos reales. En este trabajo se investiga el proceso de aprendizaje de dinámicas persistentes usando redes neuronales.
H. D. Navone +2 more
doaj
Data‐Driven SuStaIn Model of Disability Progression in Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To determine whether ordinal Subtype and Stage Inference (SuStaIn) applied to routine ALSFRS‐R item scores can identify reproducible disability progression patterns in amyotrophic lateral sclerosis (ALS) and provide clinically meaningful staging.
Giammarco Milella +5 more
wiley +1 more source
MODELLING TOURISM DEMAND: A COMPARATIVE STUDY BETWEEN ARTIFICIAL NEURAL NETWORKS AND THE BOX-JENKINS METHODOLOGY [PDF]
This study seeks to investigate and highlight the usefulness of the Artificial Neural Networks (ANN) methodology as an alternative to the Box-Jenkins methodology in analysing tourism demand.
Ferreira, Joao +3 more
core
TUBERCULOSIS EN BARCELONA: MODELO PREDICTIVO BASADO EN SERIES TEMPORALES
Revista Española de Salud Pública, 2009 La tuberculosis (TB) a escala mundial sigue ocasionando cada año millones de casos nuevos y de muertes. La Organización Mundial de la Salud (OMS) ha estimado recientemente que en el 2007 se registraron 9.273.000 casos (incidencia de 139/100.000 ...
M. Pilar Muñoz +2 more
doaj