Results 131 to 140 of about 725,864 (316)
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
, 2017 Serine is a ‘‘non-essential’’ amino acid which humans can synthesise (2). Serine exists in 2 forms: L-serine and its mirror image D-serine.
Hardiman, Orla
core +1 more source
Can glycine be transformed into threonine at nonketonic hyperglycinemia?
Сибирский научный медицинский журналIn the forties of the XX century, it was stated by Rose what amino acids are essential that is they are not synthesized in the organism of man and animals if they cannot be found in food.
A. V. Malinovsky
doaj +1 more source
Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach +23 more
wiley +1 more source
Design and synthesis of a potential inhibitor for DEN2 NS2B/NS3 serine protease / Lee Yean Kee [PDF]
, 2011 This work involves searching and designing of inhibitors for DEN2 NS2B/NS3 serine protease. It comprises three phases: modeling, synthesis and screening.
Lee, Yean Kee
core
Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni +19 more
wiley +1 more source
, 1950 Artwork photographed and inventoried by the 2015 Summer Art Inventory team in the Visual Resources Center.This is an abstract painting of whites, blues, reds, and yellows. The artist’s signature, “SeRiNE” is written in the lower right corner of the piece.
Serine
core
Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang +4 more
wiley +1 more source
Metabolomic and immune alterations in long COVID patients with chronic fatigue syndrome
Frontiers in ImmunologyIntroductionA group of SARS-CoV-2 infected individuals present lingering symptoms, defined as long COVID (LC), that may last months or years post the onset of acute disease.
Suguru Saito +9 more
doaj +1 more source