Results 201 to 210 of about 938,109 (291)
The pyridoxal- and pyridoxal 5′-phosphate-catalysed non-enzymic degradations of
J. H. Thomas, K. S. Dodgson, N. Tudball
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Nrf2 isn't just a protector—it's a driver of cancer stemness. The study uncovers how arsenic‐activated Nrf2 directly upregulates KLF4, a key pluripotency factor, fueling oncogenic reprogramming. Through enhancer activation and self‐reinforcing loop, Nrf2 and KLF4 co‐opt gene networks linked to epithelial‐to‐mesenchymal transition and tumor growth ...
Ziwei Wang+9 more
wiley +1 more source
Shape sorting of two distinct amino acid residues at the multiple binding sites of a porous metal-macrocycle framework. [PDF]
Tashiro S+3 more
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A Distinct Na+-requiring Transport System for Alanine, Serine, Cysteine, and Similar Amino Acids
Halvor N. Christensen+2 more
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Wound infections induce gcFGF8a expression, which subsequently executes direct antimicrobial activity to suppress local infection while simultaneously activating the FGFR4‐mediated ERK/AKT‐mTOR signaling cascade, thereby upregulating HIF1α and enhancing glycolysis. These coordinated actions synergistically promote tissue repair by eliminating pathogens
Ya‐Zhen Hu+6 more
wiley +1 more source
Editorial - Patient perspectives on new therapies for genetic diseases. [PDF]
Elbracht M, Zweier C, Krey-Grauert I.
europepmc +1 more source
Triple‐negative breast cancer (TNBC) remains a major challenge in breast cancer management as it lacks effective therapeutic targets. This study uncovers that MYC/TET3‐regulated mitochondrial inner‐membrane protein TMEM65 promotes TNBC progression and cisplatin resistance by activating the OXPHOS‐SERPINB3 pathway and reveals TMEM65 as a potential ...
Yin‐Ling Zhang+10 more
wiley +1 more source
Nonessential amino acid is not nonessential in geriatric patients: implications for maxillofacial wound healing and bone repair. [PDF]
Kim SG.
europepmc +1 more source