Results 211 to 220 of about 652,471 (299)

L-Serine enables reducing the virulence of Acinetobacter baumannii and modulating the SIRT1 pathway to eliminate the pathogen

Jianxia Zhou, Ding-Yun Feng, Xia Li, Yuetao Chen, Min Zhang, Wenbin Wu, Jiaxin Zhu, Hui Li, Xuan‐xian Peng, Tiantuo Zhang   +9 more
openalex   +1 more source

Engineering serine metabolism to enhance AOX1 promoter self-induction in a formate dehydrogenase-deficient Komagataella phaffii [PDF]

Rocio Cozmar, Julio Berríos, Patrick Fickers   +2 more
openalex   +1 more source

Small Nucleolar RNA Snord17 Promotes Self‐Renewal of Intestinal Stem Cells through Yy2 mRNA Export and Tead4 Activation

Advanced Science, EarlyView.
Snord17, through interaction with Thoc3, promotes nuclear export and translation of Yy2 mRNA in Snord17+/+ ISCs. The Yy2 protein subsequently binds the Tead4 promoter to promote its transcription, activating Hippo signaling, which is essential for ISC maintenance.
Peikang Zhang, Yuwei Xu, Yufei Lan, Zhen Xiong, Zhibin Yi, Runyuan Wu, Cunzhen Li, Ying Du, Hui Guo, Yingchi Yang, Zusen Fan   +10 more
wiley   +1 more source

D-Serine's Journey Between Stars and Synapses. [PDF]

Neurochem Res
Mountadem S, Oliet SHR, Panatier A.
europepmc   +1 more source

Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors

Advanced Science, EarlyView.
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su, Tianqing Nie, Guofeng Chen, Muya Xiong, Yumin Zhang, Guoqing Wu, Mengyuan You, Hang Xie, Jian He, Yanchao Xiong, Hangchen Hu, Wenfeng Zhao, Minjun Li, Gengfu Xiao, Leike Zhang, Yechun Xu   +15 more
wiley   +1 more source

Protease profiling in fecal samples: a novel non-invasive diagnostic tool for gastrointestinal disorders. [PDF]

Sci Rep
Baldassar L, Cendron L, Facchin S, Redavid C, Barberio B, Jorkesh A, Dettin M, Pasquato A, Savarino EV.   +8 more
europepmc   +1 more source

The tomato gene Pti1 encodes a serine/threonine kinase that is phosphorylated by Pto and is involved in the hypersensitive response

, 1995
Jianmin Zhou, Ying-Tsu Loh, Ray A. Bressan, Gregory B. Martin   +3 more
openalex   +1 more source

Activating the Osteoblastic USP26 Pathway Alleviates Multi‐Organ Fibrosis by Decreasing Insulin Resistance

Advanced Science, EarlyView.
The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang, Wenkai Ye, Liang He, Zhou Dan, Leilei Chang, Zijie You, Yuanyue Jiang, Guoqing Tang, Lianfu Deng, Changwei Li   +9 more
wiley   +1 more source

Boron, Titanium, and Calcium Doped Graphene Monolayers for Alzheimer's Disease Biomarker Detection: A Density Functional Theory Study. [PDF]

ACS Omega
Zhou L, Luo X.
europepmc   +1 more source

Tyrosine phosphatase inhibition triggers sustained canonical serine-dependent NFκB activation via Src-dependent blockade of PP2A

, 2010
Sandra Barišić, Claudia Schmidt, Henning Walczak, Dagmar Kulms   +3 more
openalex   +2 more sources