Results 151 to 160 of about 245,013 (288)

Serine metabolism remodeling after platinum-based chemotherapy identifies vulnerabilities in a subgroup of resistant ovarian cancers. [PDF]

Nat Commun, 2022
Van Nyen T, Planque M, van Wagensveld L, Duarte JAG, Zaal EA, Talebi A, Rossi M, Körner PR, Rizzotto L, Moens S, De Wispelaere W, Baiden-Amissah REM, Sonke GS, Horlings HM, Eelen G, Berardi E, Swinnen JV, Berkers CR, Carmeliet P, Lambrechts D, Davidson B, Agami R, Fendt SM, Annibali D, Amant F.   +24 more
europepmc   +1 more source

Connexin 26 Functions as a Direct Transcriptional Regulator During the Cochlea Development

Advanced Science, EarlyView.
Connexin26 can not only form intercellular channels that mediate rapid communication on the cell membrane, but also enter the nucleus as a transcription factor to directly regulate the transcription of nuclear genes. In the developing cochlea, Cx26 can control the maturation of the molecular scissor ADAM10 by regulating the transcription of TspanC8 ...
Xiaozhou Liu, Le Xie, Yuan Jin, Sen Chen, Xinyu Shi, Yanjun Zong, Zhengdong Zhao, Wei‐Jia Kong, Yu Sun   +8 more
wiley   +1 more source

Interleukin-6 mediates PSAT1 expression and serine metabolism in TSC2-deficient cells. [PDF]

Proc Natl Acad Sci U S A, 2021
Wang J, Filippakis H, Hougard T, Du H, Ye C, Liu HJ, Zhang L, Hindi K, Bagwe S, Nijmeh J, Asara JM, Shi W, El-Chemaly S, Henske EP, Lam HC.   +14 more
europepmc   +1 more source

Effect of serine on growth performance and adipose-muscle metabolism in miR-143-deficient mice in low-protein diet [PDF]

Xingping Chen, Bo Seong Yun, Jia Chen, Jin Jun Luo, Ting Chen, Jiajie Sun, Yongliang Zhang, Qianyun Xi   +7 more
openalex   +1 more source

Single‐Cell Profiling Across Immune Tissues and Organs Reveals Immunosenescence Signatures in Male Rhesus Monkeys

Advanced Science, EarlyView.
Single‐cell profiling across bone marrow, spleen, mesenteric lymph, and blood in rhesus monkeys reveals organ Immunosenescence. GZMB rises with age, particularly in cytotoxic and terminally exhausted CD8+ T cells, and BHLHE40 emerges as a key transcription factor enriched across multiple CD8+ subsets, regulating pro‐inflammatory and exhaustion‐related ...
Shengnan Wang, Zhengna Zhu, Hongju Yang, Yaping Yan, Luyao Ran, Naixue Yang, Yichao Wang, Li Wu, Bing Bai, Weizhi Ji, Wei Si   +10 more
wiley   +1 more source

Intestinal serine protease inhibition increases FGF21 and improves metabolism in obese mice [PDF]

, 2019
Kamal Albarazanji, Matthew Jennis, Cassandre Cavanaugh, Wensheng Lang, Bhanu Singh, James C. Lanter, James M. Lenhard, Pamela J. Hornby   +7 more
openalex   +1 more source

A Trypsin‐Like Serine Protease ZmNAL1a Fine‐Tunes Maize Floral Transition and Flowering Time

Advanced Science, EarlyView.
This study identifies a trypsin‐like serine protease, ZmNAL1a, that moves from leaves to the shoot apical meristem. ZmNAL1a promotes the floral transition by degrading TOPLESS‐like corepressor REL2, which thereby enhances the expression of key flowering genes through elevating histone acetylation and relieving REL2–ZmEREBP147‐mediated transcriptional ...
Nan Li, Qiang Ning, Zhen Li, Qian Zhang, Peilu Zhu, Jimin Zhan, Yunfu Li, Zhen Li, Liang Dong, Qing Xiong, Jiahao Liao, Jie Liu, David Jackson, Munenori Kitagawa, Zuxin Zhang, Lei Liu   +15 more
wiley   +1 more source

Independent serum metabolomics approaches identify disrupted glutamic acid and serine metabolism in Parkinson's disease patients. [PDF]

NPJ Parkinsons Dis
Gervasoni J, Marino C, Imarisio A, Santucci L, Napolitano E, Nuzzo T, Yahyavi I, Avenali M, Cicchinelli M, Buongarzone G, Galandra C, Picascia M, Grimaldi M, Pacchetti C, Errico F, D'Ursi AM, Urbani A, Valente EM, Usiello A.   +18 more
europepmc   +1 more source

Reviewer #2 (Public review): Phosphoglycerate mutase regulates Treg differentiation through control of serine synthesis and one-carbon metabolism

Wesley H Godfrey, Kaho Cho, Xiaojing Deng, Chandra Shekar R Ambati, Vasanta Putluri, Abu Hena Mostafa Kamal, Nagireddy Putluri, Michael D Kornberg   +7 more
openalex   +1 more source

Integrated flux and pool size analysis in plant central metabolism reveals unique roles of glycine and serine during photorespiration

, 2022
Xinyu Fu, Luke M. Gregory, Sean E. Weise, Berkley J. Walker   +3 more
openalex   +2 more sources