Results 251 to 260 of about 372,460 (343)

Single-Chain Variable Fragments: Targeting Snake Venom Phospholipase A₂ and Serine Protease. [PDF]

Toxins (Basel)
Jia Y, Garcia A, Reyes E.
europepmc   +1 more source

Simvastatin overcomes the pPCK1‐pLDHA‐SPRINGlac axis‐mediated ferroptosis and chemo‐immunotherapy resistance in AKT‐hyperactivated intrahepatic cholangiocarcinoma

Cancer Communications, EarlyView.
Abstract Background Intrahepatic cholangiocarcinoma (ICC) is a challenging cancer with an increasing incidence. The Phase III TOPAZ‐1/KEYNOTE‐966 study demonstrated chemo‐immunotherapy (CIT) as a significant advancement, potentially replacing traditional chemotherapy for advanced biliary tract cancer.
Jinghan Zhu, Yixiao Xiong, Yuxin Zhang, Huifang Liang, Kun Cheng, Yuanxiang Lu, Guangzhen Cai, Yang Wu, Yunhui Fan, Xiaoping Chen, Hong Zhu, Zeyang Ding, Wanguang Zhang   +12 more
wiley   +1 more source

Corrigendum to "Serine protease inhibitors could be of benefit in the treatment of COVID-19 disease". [PDF]

Ther Adv Infect Dis
europepmc   +1 more source

Borrelia burgdorferi serine protease HtrA is a pleiotropic regulator of stress response, motility, flagellar hemostasis, and infectivity. [PDF]

Commun Biol
Zhang K, Sze CW, Zhao H, Liu J, Li C.
europepmc   +1 more source

Upregulation of a lymphoid serine protease in kidney allograft recipients

, 1990
Gere Sunder‐Plassmann, Ludwig Wagner, K Hrubý, P Balcke, C. P. Worman   +4 more
openalex   +1 more source

Ubiquitination in cancer: mechanisms and therapeutic opportunities

Cancer Communications, EarlyView.
Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu, Xu Zhang, Waner Liu, Zhe Zhou, Siyu Xiong, Jie Li, Xiang Chen, Cong Peng   +7 more
wiley   +1 more source

The serine protease DPP9 and the redox sensor KEAP1 form a mutually inhibitory complex. [PDF]

J Biol Chem
Tsamouri LP, Hsiao JC, Bachovchin DA.
europepmc   +1 more source

Promising Prodiginins Biological Activities

Chemistry &Biodiversity, EarlyView.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto, Melisa E. Gantner, Boris E. Rodenak‐Kladniew, Santiago Rodriguez, María L. Cuestas, Alan Talevi, Guillermo R. Castro   +6 more
wiley   +1 more source

Macrocyclic Inhibitors Targeting the Prime Site of the Fibrinolytic Serine Protease Plasmin. [PDF]

ChemMedChem
Wiedemeyer SJA, Wu G, Lang-Henkel H, Whisstock JC, Law RHP, Steinmetzer T.   +5 more
europepmc   +1 more source

The Serine Protease Inhibitors TLCK and TPCK React with the RB-Binding Core of HPV-18 E7 Protein and Abolish Its RB-Binding Capability

, 1996
Hubert Stöppler, Melissa C. Stoppler, A.J. Adduci, DEBRA KOVAL, Richard Schlegel   +4 more
openalex   +1 more source