Results 261 to 270 of about 425,250 (334)

Quantitative proteomics identifies clusterin as a novel biomarker for atherosclerosis

Animal Models and Experimental Medicine, EarlyView.
This schematic illustrates the proposed mechanism. In advanced atherosclerotic lesions, upregulated CLU on the cell surface activates low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1). This interaction triggers the phosphorylation and activation of AKT.
Dengfeng Ding, Yingjie Zhang, Li Zhang, Xinou Zheng, Miaomiao Niu, Yunxiao Jia, Xuezhuang Li, Hua Chen, Chao Guo, Tao Jiang, Yuqiong Zhao   +10 more
wiley   +1 more source

Autologous Paracrine Prostasin-Matriptase Serine Protease Interaction in Lymphoid Cancer Cells. [PDF]

Cells
Chen LM, Chai KX.
europepmc   +1 more source

Back Again to the Future: A New Era for Cerebroprotection

Annals of Neurology, EarlyView.
Cerebroprotection is a fresh framework for designing neurological therapy that targets glia and vascular cells, in addition to neurons. In the future, successful cerebroprotection will involve targeting all elements of the neurovascular unit. Preclinical trials must include functional outcomes, as well as lesion morphometry.
Patrick Lyden
wiley   +1 more source

Cathepsin L and transmembrane serine protease 11E mediate trypsin-independent entry of porcine deltacoronavirus into Huh7 cells. [PDF]

J Virol
Xiao W, Xiong Y, Wang Y, Li T, Chen C, Shi Y, Su G, Zhou Y, Xiao S, Fang L.   +9 more
europepmc   +1 more source

Inhibition of ferroptosis by serine protease inhibitor attenuates acute respiratory distress syndrome

Qinyue Guo, Xiao-Ming Gao, Jiajia Ren, Guorong Deng, Ruohan Li, Chuchu Zhang, Xi Xu, Jiamei Li, Wei Liu, Lingzhi Qin, Gang Wang   +10 more
openalex   +1 more source

Plasma Proteomics Identifies TAOK3 as a Potential Biomarker of Rheumatoid Arthritis Activity and a Novel Therapeutic Target

Arthritis &Rheumatology, Accepted Article.
Objective Bone destruction associated with active rheumatoid arthritis (RA) remains a major therapeutic challenge, with a lack of reliable molecular markers reflecting bone injury. This study aims to identify novel biomarkers linked to bone destruction in active RA through proteomic analysis, providing new strategies for precise monitoring and targeted
Pengfei Xin, Wenzhen Li, Xinyu A, Jun Shen, Xiaohui Meng, Yanqin Bian, Haihui Han, Zheng Xiang, Lei Ran, Songtao Sun, Jun Xie, Tao Yue, Qi Zhu, Xiaoming Zhang, Lu Xie, Lianbo Xiao   +15 more
wiley   +1 more source

Pretreatment with serine protease inhibitors impairs Leishmania amazonensis survival on macrophages. [PDF]

Parasit Vectors
de Almeida Machado P, Gomes PS, Coimbra ES, de Matos Guedes HL.   +3 more
europepmc   +1 more source

Integrative single cell RNA‐sequencing and spatial transcriptomics uncovers distinct macrophage‐fibroblast cross‐talk in human hip synovium between patients with femoroacetabular impingement and osteoarthritis

Arthritis &Rheumatology, Accepted Article.
Objectives Femoroacetabular impingement (FAI) and synovitis have been recognized as essential factors for developing osteoarthritis (OA) in the hip joints. However, little is known about altered synovial cellular compositions, their associated transcriptomic profiles, and cell‐cell interactions in FAI and hip OA.
Gulzada Kulzhanova, Alexis Klee, Mina Botros, Victoria L. Hansen, John Reuter, Eliya Tazreena Tashbib, Eloise Fadial, Benjamin F. Ricciardi, Brian Giordano, Chia‐Lung Wu   +9 more
wiley   +1 more source

Design, Synthesis, and Biological Activity of m-Tyrosine-Based 16- and 17-Membered Macrocyclic Inhibitors of Hepatitis C Virus NS3 Serine Protease

, 2005
Kevin X. Chen, F. George Njoroge, John Pichardo, Andrew Prongay, Nancy Butkiewicz, Nanhua Yao, Vincent Madison, Viyyoor Girijavallabhan   +7 more
openalex   +1 more source

Valorization of fishing industry by‐products for biodiesel production: Unlocking the potential of residual fish oil

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract Fishing waste and its by‐products, whether naturally occurring or generated by the processing industry, represent a significant opportunity for producing high‐value products. These often discarded or underutilized residues can be converted into various valuable products through advanced processing technologies. Among the potential products are
Patrick da Silva Sousa, Francisco Simão Neto, Paulo Gonçalves de Sousa Junior, Francisco Izaias da Silva Aires, Calebe da Rocha Silva, Kaiany Moreira dos Santos, Viviane de Castro Bizerra, Maria Alexsandra Sousa Rios, José Cleiton Sousa dos Santos   +8 more
wiley   +1 more source