The serine protease DPP9 and the redox sensor KEAP1 form a mutually inhibitory complex. [PDF]
Tsamouri LP, Hsiao JC, Bachovchin DA.
europepmc +1 more source
Targeted genome mining identified thermostable enzymes (PETases) that hydrolyze the commonly used plastic polymer polyethylene terephthalate (PET). Thermostable enzymes are identified from thermophilic microbial sources. Experimental results reveal enzymatic activity on authentic PET films, highlighting potential for industrial application.
Zhenyu Hu+4 more
wiley +1 more source
Macrocyclic Inhibitors Targeting the Prime Site of the Fibrinolytic Serine Protease Plasmin. [PDF]
Wiedemeyer SJA+5 more
europepmc +1 more source
Proteoglycans (PGs) play roles in many important biological events including growth factor signaling, wound repair, blood coagulation, brain development, and neural stem cell migration. As the glycosaminoglycan chain of PGs is attached to the core protein through a tetrasaccharide linkage region, it is important to decipher the intricate control of the
Po-han Lin, Xuefei Huang
wiley +1 more source
Redox and solvent-stable alkaline serine protease from <i>Bacillus patagoniensis</i> DB-5: heterologous expression, properties, and biotechnological applications. [PDF]
Li Z, Xing Y, Liu P, Liao W, Miao L.
europepmc +1 more source
The Molecular Toolbox for Linkage Type‐Specific Analysis of Ubiquitin Signaling
Ubiquitin modifications regulate virtually all aspects of eukaryotic cell biology through an array of polyubiquitin chain signals that adopt distinct structures, enabling the individual polyubiquitin linkages to mediate specific functions in cells.
Julian Koch+3 more
wiley +1 more source
Corrigendum to "Serine protease inhibitors could be of benefit in the treatment of COVID-19 disease". [PDF]
europepmc +1 more source
To be, or not to be cleaved: Directed evolution of a canonical serine protease inhibitor against active and inactive protease pair identifies binding loop residue critical for prevention of proteolytic cleavage. [PDF]
Köller Z+8 more
europepmc +1 more source