Results 261 to 270 of about 422,331 (334)

Comparison of structures and inhibition activities of serine protease inhibitors of Trichinella spiralis and Trichinella pseudospiralis. [PDF]

Cell Biosci
Li R, Zhang B, Chen C.
europepmc   +1 more source

Exploiting Subsite S1 of Trypsin-Like Serine Proteases for Selectivity:  Potent and Selective Inhibitors of Urokinase-Type Plasminogen Activator

, 2001
Richard L. Mackman, B.A. Katz, J. Guy Breitenbucher, Hon C. Hui, Erik Verner, Christine Luong, Liang Liu, Paul A. Sprengeler   +7 more
openalex   +1 more source

Navigating adverse immunostimulation: A practical guide for clinical researchers

British Journal of Clinical Pharmacology, EarlyView.
Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort, Anouk C. Meijs, Naomi B. Klarenbeek, Matthijs Moerland   +3 more
wiley   +1 more source

Investigation on the Substrate Specificity of Serine Protease Neuropsin by Molecular Dynamics Simulation and Marmoset Gene Atlas (MGA). [PDF]

ACS Omega
Lintuluoto M, Horioka Y, Fujiwara M, Abe M, Fukunishi Y, Tamura H, Lintuluoto JM.   +6 more
europepmc   +1 more source

Serine Protease EspP from Enterohemorrhagic Escherichia Coli Is Sufficient to Induce Shiga Toxin Macropinocytosis in Intestinal Epithelium

, 2013
Julie In, Valeriy Lukyanenko, Jennifer Foulke‐Abel, Ann L. Hubbard, Michael Delannoy, Anne-Marie Hansen, James B. Kaper, Nadia Boisen, James P. Nataro, Chengru Zhu, Edgar C. Boedeker, Jorge A. Girón, Olga Kovbasnjuk   +12 more
openalex   +2 more sources

A Stable Bioisostere of Ester‐Linked Ubiquitin Chains Enables Decoding of Protein Interactors

ChemBioChem, EarlyView.
An ester‐to‐amide analog of an ester‐linked ubiquitin dimer is chemically synthesized through a convergent approach involving the sequential chemoselective ligation of three peptide fragments generated through Fmoc‐based solid‐phase peptide synthesis. The hydrolysis‐resistant ubiquitin dimer served as a chemical probe in the identification of potential
Yoshinori Taguchi, Takuya Tomita, Takuma Nishizawa, Dai Nakamura, Showmitra Saha, Takanori Oyoshi, Kohei Sato, Nobuyuki Mase, Yasushi Saeki, Tetsuo Narumi   +9 more
wiley   +1 more source

Monoclonal antibody neutralizes <i>Staphylococcus aureus</i> serine protease-like protein B (SplB)-induced pathology. [PDF]

Infect Immun
Iqbal J, von Fournier J, Wittmann N, Darisipudi MN, Mrochen DM, Smiljanov B, Surmann K, Wockenfuß G, Steil L, Kohler TP, Glinka FL, Peringathara S, Saade C, Fernandes LM, Bornscheuer U, Reichel CA, Bröker BM, Raafat D, Holtfreter S.   +18 more
europepmc   +1 more source

Advances in Parahydrogen‐Induced Polarization for Nuclear Magnetic Resonance of Peptides, Proteins, and Biopolymers

ChemistryEurope, EarlyView.
Hyperpolarization by parahydrogen‐induced polarization enhances the sensitivity of nuclear magnetic resonance spectroscopy of amino acids, peptides, mini‐proteins, and biopolymers using nonnatural amino acids with unsaturated side chains up to three orders of magnitude.
Gerd Buntkowsky
wiley   +1 more source

[Pathogenesis and mechanism of serine protease 23 in skin fibrosis of systemic sclerosis]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Yuan X, Li Z, Xu D, Li T, Fang D, Mu R.
europepmc   +1 more source