Results 271 to 280 of about 358,313 (362)

Transcription of the Rat Serine Protease Inhibitor 2.1 Gene in Vivo: Correlation with GAGA Box Promoter Occupancy and Mechanism of Cytokine-Mediated Down-Regulation [PDF]

, 1998
Anne Emmanuelle Simar-Blanchet, Catherine Legraverend, J. Thissen, Alphonse Le Cam   +3 more
openalex   +1 more source

Degradation of Nonribosomal Peptide Synthetase Megasynthetases SrfAA and SrfAB by Acyldepsipeptide‐Activated ClpP in Bacillus Subtilis

ChemBioChem, EarlyView.
FtsZ is the only target protein that has been biochemically confirmed to be hydrolyzed both in vitro and in bacterial cells. Coupled with activity‐based protein profiling of nonribosomal peptide synthetases, the ClpP‐ADEP1 proteolytic complex that degrades the surfactin synthetases SrfAA and SrfAB in cell lysates and bacterial cells is demonstrated ...
Fumihiro Ishikawa, Chiharu Uchida, Rina Ohnishi, Taketo Imai, Genzoh Tanabe   +4 more
wiley   +1 more source

Neutrophils from patients with acquired neutropenia exhibit alterations in serine protease immunostaining and activity. [PDF]

Br J Haematol
Mazur A, Skrzeczynska-Moncznik J, Mavroudi I, Perraki CM, Korkmaz B, Papadaki HA, Cichy J.   +6 more
europepmc   +1 more source

Assignment<footref rid="foot01">¹</footref> of the gene encoding the neuronal multidomain serine protease neurotrypsin (PRSS12) to human chromosome band 4q25→q26 by in situ hybridization [PDF]

, 1999
Serguei Kozlov, Mariluce Riegel, Jochen Kinter, G. Hintsch, Paolo Cinelli, Albert Schinzel, P. Sonderegger   +6 more
openalex   +1 more source

Profiling Serine Hydrolases in the Leishmania Host‐Pathogen Interactome Using Cell‐Permeable Activity‐Based Fluorophosphonate Probes

ChemBioChem, Accepted Article.
Leishmaniasis, a vector borne neglected tropical disease, caused by the protozoan parasite Leishmania, is a major global public health challenge with millions of new cases annually. Treatment of leishmaniasis is difficult for many reasons including a multiple life‐cycle stages, involving both an infective insect vector form, the promastigote, and a ...
Jaime A. Isern, Exequiel O.J. Porta, Karunakaran Kalesh, Zisis Koutsogiannis, Davide Cazzola, Ehmke Pohl, Paul Denny, Patrick G. Steel   +7 more
wiley   +1 more source

Microsporidian Nosema bombycis secretes serine protease inhibitor to suppress host cell apoptosis via Caspase BmICE. [PDF]

PLoS Pathog
Ran M, Bao J, Li B, Shi Y, Yang W, Meng X, Chen J, Wei J, Long M, Li T, Li C, Pan G, Zhou Z.   +12 more
europepmc   +1 more source

The sequence and reactive site of ecotin. A general inhibitor of pancreatic serine proteases from Escherichia coli.

, 1991
Marisa E. McGrath, Wade Hines, Judy A. Sakanari, R.J. Fletterick, Charles S. Craik   +4 more
openalex   +1 more source

Nematode serine protease inhibitor SPI-I8 negatively regulates host NF-κB signalling by hijacking MKRN1-mediated polyubiquitination of RACK1. [PDF]

Commun Biol
Wu F, Chen Y, Chen X, Tong D, Zhou J, Du Z, Yao C, Yang Y, Du A, Ma G.   +9 more
europepmc   +1 more source

Design and Evaluation of Bivalent K‐Ras Inhibitors That Target the CAAX Binding Site and the Acidic Surface of Farnesyltransferase and Geranylgeranyltransferase I

Chemistry – A European Journal, EarlyView.
Chemical inhibition of K‐Ras posttranslational prenylation represents a promising strategy against aggressive cancers. A structure‐based design produces piperidine‐based peptidomimetics conjugated to cationic modules, effectively inhibiting FTase and GGTase I at single‐digit nanomolar concentrations.
Naomi Horiuchi, Rania Omer, Fumitoshi Sugino, Naomi Ogino, Yoshihisa Inoue, Kazi Aslamuzzaman, Takeyuki Suzuki, Said M. Sebti, Junko Ohkanda   +8 more
wiley   +1 more source

Identification of the interaction between MAPK1 and Eimeria acervulina serine protease inhibitor: a preliminary functional study. [PDF]

Acta Biochim Biophys Sin (Shanghai)
Lian L, Sun H, Wang J, Li W, Sheng Y, Gong X, Sun Q, Wang P, Zheng Y, Song H.   +9 more
europepmc   +1 more source