Results 281 to 290 of about 372,460 (343)

A signaling pathway, independent of the oxidative burst, that leads to hypersensitive cell death in cultured tobacco cells includes a serine protease

, 1999
Akira Yano, Kaoru Suzuki, Hideaki Shinshi   +2 more
openalex   +1 more source

The PP2A‐B56 Binding Site LxxIxE Contributes to Asp‐Mediated Spindle Pole Stability

Cytoskeleton, EarlyView.
ABSTRACT The organization of microtubules into a mitotic spindle is critical for animal cell proliferation and involves the cooperation of hundreds of proteins whose molecular roles and regulation are not fully understood. The protein product of the Drosophila gene abnormal spindle, Asp, is a microtubule‐associated protein required for correct mitotic ...
Margaux Quiniou, Maria C. Burns, Aynsley McDermott, Karolina Jaworek, Stacey J. Scott, James G. Wakefield, Lori Borgal   +6 more
wiley   +1 more source

Cutaneous Melanoma: An Overview of Physiological and Therapeutic Aspects and Biotechnological Use of Serine Protease Inhibitors. [PDF]

Molecules
Boleti APA, Jacobowski AC, Monteiro-Alfredo T, Pereira APR, Oliva MLV, Maria DA, Macedo MLR.   +6 more
europepmc   +1 more source

The Cortical Granule Serine Protease CGSP1 of the Sea Urchin, Strongylocentrotus purpuratus, Is Autocatalytic and Contains a Low-Density Lipoprotein Receptor-like Domain

, 1999
Sheila A. Haley, Gary M. Wessel
openalex   +1 more source

PLK4: Master Regulator of Centriole Duplication and Its Therapeutic Potential

Cytoskeleton, EarlyView.
ABSTRACT Centrosomes catalyze the assembly of a microtubule‐based bipolar spindle, essential for the precise chromosome segregation during cell division. At the center of this process lies Polo‐Like Kinase 4 (PLK4), the master regulator that controls the duplication of the centriolar core to ensure the correct balance of two centrosomes per dividing ...
Muhammad Hamzah, Franz Meitinger, Midori Ohta   +2 more
wiley   +1 more source

Serine protease inhibitor, SerpinA3n, regulates cardiac remodelling after myocardial infarction. [PDF]

Cardiovasc Res
Sun Q, Chen W, Wu R, Tao B, Wang P, Sun B, Alvarez JF, Ma F, Galindo DC, Maroney SP, Saviola AJ, Hansen KC, Li S, Deb A.   +13 more
europepmc   +1 more source

Pharmacokinetic and Bioequivalence Evaluation of Two Sitagliptin Tablets With Different Salts in Healthy Subjects

Clinical Pharmacology in Drug Development, EarlyView.
Abstract The objective of the current study was to evaluate the rate and extent of absorption of a test formulation (sitagliptin hydrochloride) and a reference formulation (sitagliptin phosphate). An open‐label, randomized, single‐dose, single‐center, 2‐sequence, 2‐period, and cross‐over phase 1 study was implemented to assess the pharmacokinetic ...
Usok Hyun, Seongnam Chu, Sungyun Kim, Jung‐Ki Hong, Taeyoung Kim, In‐Soo Yoon, Jung‐Jin Kim, Hyun‐Jong Cho   +7 more
wiley   +1 more source

Therapeutic potential of the secreted Kazal-type serine protease inhibitor SPINK4 in colitis. [PDF]

Nat Commun
Wang Y, Han J, Yang G, Zheng S, Zhou G, Liu X, Cao X, Li G, Zhang B, Xie Z, Li L, Zhang M, Li X, Chen M, Zhang S.   +14 more
europepmc   +1 more source

Annual Banned‐Substance Review 17th Edition—Analytical Approaches in Human Sports Drug Testing 2023/2024

Drug Testing and Analysis, EarlyView.
Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario  Thevis, Tiia  Kuuranne, Hans  Geyer   +2 more
wiley   +1 more source

Identification of the interaction between MAPK1 and <i>Eimeria acervulina</i> serine protease inhibitor: a preliminary functional study. [PDF]

Acta Biochim Biophys Sin (Shanghai)
Lian L, Sun H, Wang J, Li W, Sheng Y, Gong X, Sun Q, Wang P, Zheng Y, Song H.   +9 more
europepmc   +1 more source