Results 301 to 310 of about 372,460 (343)

GEO combined with quantitative protein trait loci identify causative proteins in hypertrophic cardiomyopathy

ESC Heart Failure, EarlyView.
Abstract Aims Hypertrophic cardiomyopathy (HCM) is a rare genetic heart disease characterized by a limited patient population and scarce research and treatment resources. This study aimed to identify HCM‐associated proteins by integrating cardiac tissue data from the Gene Expression Omnibus (GEO) database with the latest protein quantitative trait ...
Bo Li, Xu Zhao, Yan Ding, Yi Zhang
wiley   +1 more source

Update on preclinical models of cancer therapy‐related cardiac dysfunction: Challenges and perspectives. A scientific statement of the Heart Failure Association (HFA) of the ESC, the ESC Council of Cardio‐Oncology, and the ESC Working Group on Cellular Biology of the Heart

European Journal of Heart Failure, EarlyView.
New anticancer therapies with potential cardiovascular side effects are continuously being introduced into clinical practice, with new and often unexpected toxicities becoming apparent only after clinical introduction. These unknown toxicities should be identified and understood beforehand to better prepare patients and physicians, enabling the ...
Alessandra Ghigo, Pietro Ameri, Aarti Asnani, Edoardo Bertero, Rudolf A. de Boer, Dimitrios Farmakis, Arantxa González, Stephane Heymans, Borja Ibáñez, Teresa López‐Fernández, Alexander R. Lyon, Piero Pollesello, Amina Rakisheva, Konstantinos Stellos, Katrin Streckfuss‐Bömeke, Carlo Gabriele Tocchetti, Thomas Thum, Peter van der Meer, Eva Van Rooij, Piotr Ponikowski, Marco Metra, Giuseppe Rosano, Sophie Van Linthout   +22 more
wiley   +1 more source

High-temperature requirement serine protease A2 inhibitor UCF-101 ameliorates damaged neurons in traumatic brain-injured rats by the AMPK/NF-κB pathway. [PDF]

Open Life Sci
Qiu TW, Jin Z, Fu ZZ, Yan XJ, Zhan CP, Zheng HW, Li MY, Yu GF.   +7 more
europepmc   +1 more source

Serine protease RAYM_01812 (SspA) inhibits complement-mediated killing and monocyte chemotaxis and contributes to virulence of <i>Riemerella anatipestifer</i> in ducks. [PDF]

Virulence
Yang R, Li S, Guo J, Wang Y, Dong Z, Wang Q, Bai H, Ning C, Zhu X, Bai J, Hu S, Xiao Y, Li Z, Zhou Z.   +13 more
europepmc   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Actinidia spp. (Kiwifruit): A Comprehensive Review of Its Nutraceutical Potential in Disease Mitigation and Health Enhancement

Food Frontiers, EarlyView.
Nutraceutical Potential in Disease Mitigation and Health Enhancement of Actinidia spp. (Kiwifruit) ABSTRACT This review offers an in‐depth exploration of the Actinidia species (kiwifruit) nutritional composition, the pivotal role of its primary bioactive compounds, and their potential applications across the aforementioned health concerns. Furthermore,
Allah Rakha, Nida Rehman, Rimsha Anwar, Hina Rasheed, Roshina Rabail, Zuhaib F. Bhat, Amin Mousavi Khaneghah, Rana Muhammad Aadil   +7 more
wiley   +1 more source

Characterization of the Serine Protease TlSP1 from Trichoderma longibrachiatum T6 and Its Function in the Control of Heterodera avenae in Wheat. [PDF]

J Fungi (Basel)
Wang X, Zhang S, Xu B.
europepmc   +1 more source

Role of Serine Protease Inhibitors A1 and A3 in Ocular Pathologies. [PDF]

Invest Ophthalmol Vis Sci
Kontoh-Twumasi R, Budkin S, Edupuganti N, Vashishtha A, Sharma S.   +4 more
europepmc   +1 more source

The fatal contribution of serine protease-related genetic variants to COVID-19 outcomes. [PDF]

Front Immunol
Martínez-Gómez LE, Martinez-Armenta C, Tusie-Luna T, Vázquez-Cárdenas P, Vidal-Vázquez RP, Ramírez-Hinojosa JP, Gómez-Martín D, Vargas-Alarcón G, Posadas-Sánchez R, Fragoso JM, de la Peña A, Rodríguez-Pérez JM, Mata-Miranda MM, Vázquez-Zapién GJ, Martínez-Cuazitl A, Martínez-Ruiz FJ, Zayago-Angeles DM, Ramos-Tavera L, Méndez-Aguilera A, Camacho-Rea MDC, Ordoñez-Sánchez ML, Segura-Kato Y, Suarez-Ahedo C, Olea-Torres J, Herrera-López B, Pineda C, Martínez-Nava GA, López-Reyes A.   +27 more
europepmc   +1 more source

Cathepsin C inhibition reduces neutrophil serine protease activity and improves activated neutrophil-mediated disorders. [PDF]

Nat Commun
Nishibata Y, Arai S, Taniguchi M, Nakade I, Ogawa H, Kitano S, Hosoi Y, Shindo A, Nishiyama R, Masuda S, Nakazawa D, Tomaru U, Shimizu T, Sinko W, Nagakura T, Terada Y, Ishizu A.   +16 more
europepmc   +1 more source