Results 301 to 310 of about 358,313 (362)

Serine protease RAYM_01812 (SspA) inhibits complement-mediated killing and monocyte chemotaxis and contributes to virulence of <i>Riemerella anatipestifer</i> in ducks. [PDF]

Virulence
Yang R, Li S, Guo J, Wang Y, Dong Z, Wang Q, Bai H, Ning C, Zhu X, Bai J, Hu S, Xiao Y, Li Z, Zhou Z.   +13 more
europepmc   +1 more source

The Cortical Granule Serine Protease CGSP1 of the Sea Urchin, Strongylocentrotus purpuratus, Is Autocatalytic and Contains a Low-Density Lipoprotein Receptor-like Domain

, 1999
Sheila A. Haley, Gary M. Wessel
openalex   +1 more source

Novel para‐phenylenediamine‐based derivatives as Receptor Tyrosine Kinase‐like Orphan Receptor 1 (ROR1) Inhibitors: An in vitro preliminary characterization

ChemMedChem, Accepted Article.
ROR1 kinase is an underexplored promising target for the development of novel anticancer drugs, being strongly expressed in several cancer cell lines, but poorly in non‐tumor cells. This property, together with the scarce number of molecules effective against ROR1, led us to design and develop a research program aimed to the discovery of new chemical ...
Gerardina Smaldone, Maria Rosaria Miranda, Francesca Di Matteo, Valeria Napolitano, Michela Aliberti, Simona Musella, Veronica Di Sarno, Gianluigi Lauro, Giuseppe Bifulco, Giacomo Pepe, Giovanna Aquino, Mario Felice Tecce, Isabel Maria Gomez-Monterrey, Pietro Campiglia, Carmine Ostacolo, Alessia Bertamino, Vincenzo Vestuto, Tania CIAGLIA   +17 more
wiley   +1 more source

cFLIP - An interacting partner and a novel substrate for pro-apoptotic serine protease HtrA2. [PDF]

Biochem Biophys Rep
Natu K, Dutta S, Bose K.
europepmc   +1 more source

A Phase 1C, Open Label, Single Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of DM199 Administered Intravenously with a Polyvinyl Chloride Bag in Adult Healthy Subjects and Adults Recently Taking Angiotensin‐Converting Enzyme Inhibitors

Clinical Pharmacology in Drug Development, EarlyView.
Abstract This small phase 1C, open‐label, single ascending dose study evaluated the safety, tolerability, and pharmacokinetics (PKs) of DM199, a recombinant form of human tissue kallikrein‐1 (KLK1). A small sample size of both healthy subjects and hypertensive adults recently taking angiotensin‐converting enzyme inhibitors was studied. KLK1 has a known
Michael Giuffre, Annette D. Lista, Nick Paulson, Lorianne Masuoka   +3 more
wiley   +1 more source

Annual Banned‐Substance Review 17th Edition—Analytical Approaches in Human Sports Drug Testing 2023/2024

Drug Testing and Analysis, EarlyView.
Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario  Thevis, Tiia  Kuuranne, Hans  Geyer   +2 more
wiley   +1 more source

Characterization of the Serine Protease TlSP1 from Trichoderma longibrachiatum T6 and Its Function in the Control of Heterodera avenae in Wheat. [PDF]

J Fungi (Basel)
Wang X, Zhang S, Xu B.
europepmc   +1 more source

Comparison of Cysteine and Serine Protease Inhibitors on Dynorphin B-Induced Antinociception in the Mouse Capsaicin Test

, 1997
Koichi Tan‐No, Aki Taira, Makoto Inoue, Kiyoshi Ohshima, Tsukasa Sakurada, Chikai Sakurada, Ingrid Nylander, H.U. Demuth, Jerzy Silberring, Lars Terenius, Yuji Abe, Takeshi Tadano, Kensuke Kisara   +12 more
openalex   +2 more sources

Role of Serine Protease Inhibitors A1 and A3 in Ocular Pathologies. [PDF]

Invest Ophthalmol Vis Sci
Kontoh-Twumasi R, Budkin S, Edupuganti N, Vashishtha A, Sharma S.   +4 more
europepmc   +1 more source

β‐Catenin localization in the ctenophore Mnemiopsis leidyi suggests an ancestral role in cell adhesion and nuclear function

Developmental Dynamics, EarlyView.
Abstract Background The emergence of multicellularity in animals marks a pivotal evolutionary event, which was likely enabled by molecular innovations in the way cells adhere and communicate with one another. β‐Catenin is significant to this transition due to its dual role as both a structural component in the cadherin–catenin complex and as a ...
Brian M. Walters, Lucas J. Guttieres, Mayline Goëb, Stanley J. Marjenberg, Mark Q. Martindale, Athula H. Wikramanayake   +5 more
wiley   +1 more source