Results 41 to 50 of about 67,209 (213)

Meningococcal and pneumococcal meningitis in Northern Ghana [PDF]

, 2008
Despite improvements in technology, treatments and understanding of how bacterial meningitis develops, the disease remains a potentially life-threatening emergency capable of causing significant morbidity and mortality. N. meningitidis, S.
Forgor, Abdulai Adams
core   +1 more source

DNA methylation assessed by SMRT sequencing is linked to mutations in Neisseria meningitidis isolates [PDF]

, 2015
The Gram-negative bacterium Neisseria meningitidis features extensive genetic variability. To present, proposed virulence genotypes are also detected in isolates from asymptomatic carriers, indicating more complex mechanisms underlying variable ...
Gerd Pluschke, Christoph D. Schmid (72046), Schmid, Christoph D., Mane, Shrikant, Korlach, Jonas, Tyson A. Clark (105783), Katharina Röltgen, Wang, Guilin, Araceli Lamelas, Jonas Korlach (105788), Shrikant Mane, Araceli Lamelas (128475), Christoph D Schmid, Mohamad R Abdul Sater, Clark, Tyson A., Röltgen, Katharina, Gerd Pluschke (7855), Katharina Röltgen (120045), Guilin Wang, Sater, Mohamad R. Abdul, Tyson A Clark, Mohamad R. Abdul Sater (836669), Jonas Korlach, Guilin Wang (37620), Shrikant Mane (106631), Lamelas, Araceli, Pluschke, Gerd   +26 more
core   +1 more source

Evolution of Sequence Type 4821 Clonal Complex Meningococcal Strains in China from Prequinolone to Quinolone Era, 1972–2013

Emerging Infectious Diseases, 2018
The expansion of hypervirulent sequence type 4821 clonal complex (CC4821) lineage Neisseria meningitidis bacteria has led to a shift in meningococcal disease epidemiology in China, from serogroup A (MenA) to MenC.
Qinglan Guo, Mustapha M. Mustapha, Mingliang Chen, Di Qu, Xi Zhang, Min Chen, Yohei Doi, Minggui Wang, Lee H. Harrison   +8 more
doaj   +1 more source

Chemoenzymatic Synthesis of Well‐Defined α(2,8)‐ and α(2,9)‐Linked Oligosialosides

Angewandte Chemie, Volume 138, Issue 36, 1 September 2026.
Well‐defined α(2,8)‐ and α(2,9)‐linked oligosialic acids of different lengths can be prepared by employing recombinant bacterial polysialyltransferases in combination with chemically modified CMP‐Neu5Ac derivatives. After transfer, a sialoside is formed bearing an artificial entity, which blocks further glycosylation.
Jelle A. Fok, Keshav Kishor, Mehman I. Bunyatov, Gerlof P. Bosman, Geert‐Jan Boons   +4 more
wiley   +2 more sources

Laboratory‐Acquired Serogroup A Meningococcal Meningitis

Journal of Occupational Health, 2007
Neisseria meningitidis causes fulminant meningitis and sepsis. Worldwide, N. meningitidis serogroup A is responsible for large epidemic outbreaks (e.g., subSaharan Africa) and serogroups B, C, Y and W-135 cause epidemic and endemic disease. Meningococci are usually transmitted from person to person through close contact with contaminated aerosols and ...
Kessler, Alexander Tkeshelashvili, Stephens, David S., Somani, Jyoti   +2 more
openaire   +3 more sources

Phylogenetic Characterization of the Palyam Serogroup Orbiviruses [PDF]

Viruses, 2019
The Palyam serogroup orbiviruses are associated with abortion and teratogenesis in cattle and other ruminants. Of the 13 different serotypes that have been identified, the full genome sequence of only one, Kasba, has been published. We undertook to perform Next Generation Sequencing (NGS) and phylogenetic analysis on 12 Palyam serotypes plus field ...
Karen Ebersohn, Peter Coetzee, Louwrens P. Snyman, Robert Swanepoel, Estelle H. Venter   +4 more
openaire   +4 more sources

Insights on the Pooled Prevalence and Global Distribution of Leptospirosis in Goats: Systematic Review and Meta-Analysis

Microorganisms
Leptospira spp. infection in small ruminants is usually asymptomatic or presents nonspecific clinical signs and has an economic impact on goat farming and public health. The aim of this study was to carry out a systematic review with meta-analysis on the
Roseane de Araújo Portela, Clécio Henrique Limeira, José Artur Brilhante Bezerra, Camila Marinelli Martins, Diego Figueiredo da Costa, Carolina de Sousa Américo Batista Santos, Clebert José Alves, Sérgio Santos de Azevedo   +7 more
doaj   +1 more source

Analyzying the documented results by using microscopic agglutination test to examine sera from patients suspected of leptospirosis

Инфекция и иммунитет, 2022
Leptospirosis holds one of the leading places among zoonoses due to the breadth of distribution of natural and economic foci, as well as the severity of the clinical manifestation and mortality rate.
A. P. Samsonova, E. M. Petrov, O. V. Savelyeva, A. E. Ivanova, N. E. Sharapova   +4 more
doaj   +1 more source

Rewriting Tumor Immunity With Bacterial Membrane Vesicles: A Versatile and Potent Therapeutic Strategy

Advanced NanoBiomed Research, EarlyView.
Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi, Md Mijanur Rahman, Asma Talukder, Urooj Yousaf Virk, Jennifer C. Wilson, Nigel McMillan, Ming Q. Wei   +6 more
wiley   +1 more source

Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential

Angewandte Chemie International Edition, EarlyView.
Anti‐glycan antibodies are essential in health and disease. Access to novel glycan structures paves the way for progress in antibody profiling for biomarker discovery, antibody development, and vaccine design. We summarize the strategies to synthesize and utilize synthetic glycans for the development and application of anti‐glycan antibodies in basic ...
Fabienne Weber, Aina Valenti, Jiří Ledvinka, Oren Moscovitz, Peter H. Seeberger   +4 more
wiley   +1 more source