American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Gaucher disease (GD) is a rare lysosomal storage disorder characterized by multisystemic involvement. With the advent of enzyme replacement therapy (ERT), patient survival has improved, revealing new long‐term complications. We report a case of a 4‐year‐old male with severe neurovisceral GD who developed protein‐losing enteropathy (PLE ...
Vincenza Gragnaniello +7 more
wiley +1 more source
Longitudinal Monitoring of SARS-CoV-2 IgM and IgG Seropositivity to Detect COVID-19. [PDF]
, 2020 BackgroundSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a novel beta-coronavirus that has recently emerged as the cause of the 2019 coronavirus pandemic (COVID-19).
Fitzgerald, Robert L +5 more
core
Do Skin Prick Tests Predict Nasal Provocation Test Outcomes in Allergic Rhinitis Patients?
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background In diagnosing allergic rhinitis (AR), conventional skin prick tests (SPTs) often fail to reflect allergen‐induced nasal symptoms. Conversely, nasal provocation tests (NPTs) provide more definitive assessments but are less accessible.
Yunhyung Lee +3 more
wiley +1 more source
Infectiousness in a Cohort of Brazilian Dogs: Why Culling Fails to Control Visceral Leishmaniasis in Areas of High Transmission [PDF]
, 2002 The elimination of seropositive dogs in Brazil has been used to control zoonotic visceral leishmaniasis but with little success. To elucidate the reasons for this, the infectiousness of 50 sentinel dogs exposed to natural Leishmania chagasi infection was
Courtenay, O. +4 more
core
Persisting Transglutaminase 6 Antibodies in Neurological Gluten‐Related Disorders
Annals of Neurology, EarlyView.Objective Gluten‐related autoimmunity can cause neurological disease, although the best way to diagnose and monitor such patients is unclear. Serological testing for antibodies against transglutaminase 6 (TG6) has been proposed; however, this is not widely available in clinical practice.
Iain D. Croall +6 more
wiley +1 more source
The Results of Experimental Work upon the Serological or Precipitin Test for the Detection of Blood, Considered from the Medico-Legal Aspect [PDF]
, 1926 John Glaister
openalex +1 more source
Annals of Neurology, EarlyView.Objectives Multiple sclerosis (MS) onset risk factors include Epstein–Barr virus (EBV) indices (including host response), lower serum 25‐vitamin D (25(OH)D) levels, low sun exposure, and HLA‐DRB1*1501. The underlying molecular mechanisms are unclear. Here, we examined mediation through differential DNA methylation (DNAm) to better understand possible ...
Steve Simpson‐Yap +37 more
wiley +1 more source
Laboratory diagnosis of Chagas' heart disease
São Paulo Medical JournalThe laboratory diagnosis of Chagas' disease is a complex one. Factors relating to the host immune response and the antigenic variability of T. cruzi must be considered in the final interpretation of test results.
Antonio Walter Ferreira +1 more
doaj +1 more source
Serological Tests in Long-standing Congenital Syphilis: A CASE OF LONG-STANDING CONGENITAL SYPHILIS WITH ONLY TRACES OF ANTIBODIES IN BOTH THE STANDARD TESTS FOR SYPHILIS (STS) AND THE TREPONEMA PALLIDUM IMMOBILIZATION TEST (TPI) [PDF]
, 1959 Jan Eng
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